2015-LRN-National-Meeting-Program - APHL

2015

Laboratory

Response Network N AT I O N A L M E E T I N G

Staying Ahead of Threats

Atlanta, GA SEPTEMBER 9–11, 2015 Tom Harkin Global Communications Center

CENTERS FOR DISEASE CONTROL AND PREVENTION

P R E PA R E

DETECT

RESPOND

Table of Contents Meeting Goals and Objectives. . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Welcome. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 LRN National Meeting Planning Committee. . . . . . . . . . . . . . . . . . 4 Location Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Check-In and Information Desk Hours . . . . . . . . . . . . . . . . . . . . 10 Continuing Education Credit Information. . . . . . . . . . . . . . . . . . . 10 About LRN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 About APHL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 About CDC. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Meeting at a Glance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Program Day 1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Program Day 2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Program Day 3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 List of Posters. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 Acronyms. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Blank Note Pages. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55

Meeting Goals and Objectives The Centers for Disease Control and Prevention (CDC) Division of Preparedness and Emerging Infections (DPEI) and the National Center for Environmental Health (NCEH) in collaboration with the Association of Public Health Laboratories (APHL) is pleased to convene the 2015 Laboratory Response Network (LRN) National Meeting from September 9-11, 2015 in Atlanta, GA. The purpose of this meeting is to provide LRN stakeholders with current information on: ■■

Preparedness Collaborations

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Emerging Technologies

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Biosafety and Biosecurity

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Model Practices

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Solutions to Ongoing Challenges

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Training Needs

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Response Capabilities

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Future of the LRN

The LRN National Meeting is an ideal combination of science, policy, networking and partnerships, with a focus on innovation and emerging technologies.

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LRN 2015: Staying Ahead of Threats

Dear Colleagues: On behalf of the 2015 Laboratory Response Network (LRN) National Meeting Planning Committee, I am pleased to welcome you to Atlanta. For the first time this meeting is being held on the campus of the Centers for Disease Control and Prevention (CDC) and we’re very grateful to CDC for being such welcoming hosts. For over 15 years, the LRN has set the precedent as an exemplary laboratory system that is sustainable and capable of responding to and “Staying Ahead of Threats”, the theme for this year’s meeting. When the committee started planning this meeting, Ebola was very much on everyone’s mind and it was a reminder to us all that threats, whether biological, chemical or radiological, are always on our doorstep. This year’s meeting is comprised of plenary sessions, breakouts, and poster presentations providing opportunities to network with colleagues and to learn about the critical functions of LRN member laboratories. It is well understood that the future of the LRN relies constantly on us strengthening partnerships and realizing the value of all the laboratories that comprise the LRN. Our agenda will focus on these partnerships, the capabilities we have built and on how best to sustain and enhance these LRN achievements in the future so that we can stay ahead of threats. I would like to thank the Planning Committee for all of their efforts in developing this exciting program and to the abstract submitters, moderators and presenters for sharing their experiences and knowledge, as well as the Association of Public Health Laboratories (APHL) and CDC staff, LRN members and partners who assisted with logistics, including providing multi-media resources and tools, to help make this National Meeting a success. I would like to extend a special thank you to Mr. Tyler Wolford, APHL’s LRN Specialist for his hard work in all aspects of the meeting planning and coordination, and keeping the planning committee on target! Again, welcome and enjoy your stay in Atlanta!

Andrew Cannons, PhD

Chair, LRN National Meeting Planning Committee


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2015 LRN National Meeting Planning Committee Planning Committee Chair Andrew C. Cannons, PhD, HCLD/CC (ABB) Laboratory Director Florida Department of Health Bureau of Public Health Laboratories Tampa, FL

Planning Committee Members Blevins, Patricia, MPH Bioterrorism Laboratory Coordinator San Antonio Metropolitan Health District San Antonio, TX

Degeberg, Ruhiyyih, MPH Senior Specialist, Environmental Health Association of Public Health Laboratories Silver Spring, MD

Chaitram, Jasmine, MPH, MT (ASCP) Laboratory Preparedness and Response Branch Division of Preparedness and Emerging Infections Centers for Disease Control and Prevention

George, Karim Assistant Director Kentucky Division of Laboratory Services Frankfort, KY

Atlanta, GA Chaudhuri, Sanwat, PhD Bureau Director, Chemical and Environmental Sciences Unified State Laboratories: Public Health Utah Department of Health Taylorsville, UT Collopy, Maureen, MPH, MT (ASCP) Bioterrorism Coordinator New Hampshire Public Health Laboratories Concord, NH

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Ghuman, Harjinder Chemical Terrorism Laboratory Coordinator Georgia Public Health Laboratory Decatur, GA Griffin-Thomas, Latoya, PhD, MS Bioterrorism Response Coordinator Virginia Division of Consolidated Laboratory Services Richmond, VA Johnson, Rudolph PhD Laboratory Chief, Emergency Response Branch Division of Laboratory Sciences Centers for Disease Control and Prevention Atlanta, GA

Leonard, Pascale, PhD Molecular Biology Supervisor New Mexico Department of Health Albuquerque, NM MacKeil-Pepin, Kara Associate Specialist, Public Health Preparedness and Response Association of Public Health Laboratories Silver Spring, MD Mangal, Chris, MPH Director, Public Health Preparedness and Response Association of Public Health Laboratories Silver Spring, MD Nauschuetz, William, PhD Lab Biopreparedness Manager US Army Medical Command, Fort Sam Houston, TX Paquette, Nicholas, MS, MT (ASCP), CBSP Microbiologist Federal Bureau of Investigation Laboratory Quantico, VA

Saravia, Stefan Chemical Threat Preparedness Coordinator Minnesota Public Health Laboratory Division St. Paul, MN Tran, Robert, PhD Bioterrorism Response Coordinator Los Angeles Public Health Laboratory Downey, CA Amy Watson, PhD LRN-C Program Coordinator Centers for Disease Control and Prevention Atlanta, GA Wolford, Tyler, MS Specialist, Laboratory Response Network Association of Public Health Laboratories Silver Spring, MD Zanto, Susanne, MPH, MLS, SM Deputy Laboratory Director Montana Laboratory Services Bureau Helena, MT

Reiter-Kintz, Wanda, PhD Bioterrorism/Chemical Terrorism Coordinator State Hygienic Laboratory at the University of Iowa Coralville, IA Rhodes, Blaine, MChE Director, Office of Environmental Lab Sciences Washington Public Health Laboratories Shoreline, WA


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GENERAL INFORMATION

GENERAL INFORMATION

2015

N AT I O N A L M E E T I N G

GENERAL INFORMATION

Location Information Tom Harkin Global Communications Center Building 19 Centers for Disease Control and Prevention 1600 Clifton Road, N.E. Atlanta, GA 30333 USA 404.639.3311


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General Information Event Check-In and Information Desk Hours Located in the Tom Harkin Global Communications Center Lobby Building 19

Wednesday, September 9 8:00 a.m. – 5:00 p.m. Thursday, September 10

8:00 a.m. – 5:00 p.m.

Friday, September 11

8:00 a.m. – 1:00 p.m.

Continuing Education Credits APHL is an approved provider of continuing education programs in the clinical laboratory sciences through the American Society of Clinical Laboratory Science (ASCLS) P.A.C.E.® program. Contact hours are available for the entire conference. The contact hours to be awarded to participants who successfully complete the sessions are as follows: Day 1 of the conference—4.25 contact hours, Day 2 of the conference (either Biological OR Chemical track and general track)—5.5 contact hours and Day 3 of the conference—1.5 contact hours, for a total of 11.25 contact hours. Contact hours will only be provided for full day attendance. On Day 2 you can receive contact hours for EITHER the Biological or Chemical breakout track, not for both. You must sign in once each day on the sign-in sheets in front of the session room.

Tell Us What You Think! We take your evaluation of the LRN National Meeting seriously. Please plan on providing your feedback in an online survey provided after the meeting via email. Your feedback is vital to helping us plan a better and more beneficial meeting in the future.

Emergency Procedures for Attendees CDC and APHL encourage all attendees to review and be familiar with CDC emergency procedures, including emergency exits for all meeting rooms. Please pre-identify a location away from the Tom Harkin Global Communications Center where you and your colleagues will meet in the event of an emergency.

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About LRN The Laboratory Response Network (LRN) was established in 1999 through a collaborative effort involving founding partners, CDC, FBI, APHL and DoD to ensure an effective laboratory response to bioterrorism. Today, the LRN is an integrated network of local, state and federal public health, hospital-based, food testing, veterinary, environmental testing and international laboratories providing laboratory diagnostics and capacity for biological and chemical threats and other public health emergencies. The LRN is a unique asset in the nation’s growing preparedness for biological and chemical threats. The linking of state and local public health laboratories, veterinary, agriculture, military and water and food testing laboratories is unprecedented.

About APHL APHL is a national non-profit organization dedicated to working with members to strengthen governmental laboratories that perform testing of public health significance. Working at the national and international level, APHL advances laboratory systems and practices, promotes policies that support laboratories as a vital component of the public health system, provides a nexus for crisis response and exchange among laboratory systems, and links APHL member laboratories with federal partners, including the CDC, the Environmental Protection Agency (EPA), the Food and Drug Administration (FDA), the United States Department of Agriculture(USDA), the Department of Homeland Security (DHS) and the Federal Bureau of Investigation (FBI).

About CDC CDC is one of the major operating components of the Department of Health and Human Services (HHS). CDC’s top organizational components include the Office of the Director, Coordinating Centers and Offices and the National Institute for Occupational Safety and Health. These components collaborate to create the expertise, information and tools that people and communities need to protect their health through health promotion, prevention of disease, injury and disability and preparedness for new health threats. In addressing the preceding components of health, decisions are based on scientific excellence, requiring well-trained public health practitioners and leaders dedicated to high standards of quality and ethical practice. LRN 2015: Staying Ahead of Threats

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LRN Structure for Biological Threats Preparedness The LRN for Biological Threats Preparedness (LRN-B) is composed of three levels: Sentinel, Reference and National Laboratories. Reference laboratories are further subdivided into Reference, Standard and Advanced. The following are the capabilities for each level: National Laboratories: there are three national laboratories (1) Centers for Disease Control and Prevention, (2) United States Army Medical Research Institute for Infectious Diseases and (3) the Naval Medical Research Center. These laboratories have specialized testing capabilities (e.g. Biosafety Level 4 facilities, strain characterization) and provide test development and agent specific subject matter expertise which can be leveraged when needed by the network. Reference Laboratories: over 130 laboratories, categorized as Reference, Standard and Advanced, provide testing for high priority threat agents in a variety of matrices. In addition to their testing function, these laboratories also conduct outreach to sentinel clinical laboratories, first responders and other partners. Sentinel Laboratories: thousands of laboratories, notably hospital based, work closely with local and state public health and federal laboratories to recognize and rule-out potential biological threat agents and other emerging threats to public health. Sentinel laboratories are an integral part of the LRN with the system relying heavily on their ability to recognize rule-out and/or refer potential threats.

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LRN Structure for Chemical Threat Preparedness The LRN for Chemical Threats Preparedness (LRN-C) is composed of 53 laboratories and is categorized into three distinct levels: one, two and three. Starting with level three and building upward, each designation carries additional safety requirements and testing capabilities, in addition to the duties and requirements of the preceding level. The following are minimum capabilities required at each level: ■■

CDC Laboratories provide a high level of analysis, including a rapid toxicology screen to detect exposure to chemical threats. Further, they maintain a quality system within the LRN-C by developing methods and providing proficiency testing and exercises.

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Level 1 Laboratories provide surge capacity for CDC and can detect exposure to an expanded number of chemicals, including mustard agents, nerve agents and toxic industrial chemicals.

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Level 2 Laboratories are trained to detect exposure to a number of chemical threat agents, including cyanide, nerve agents and toxic metals.

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Level 3 Laboratories work with hospitals and first responders to maintain competency in clinical specimen collection, packaging and shipment.


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2015


FEATURED EVENTS

FEATURED EVENTS

FEATURED EVENTS

LRN 2015: Staying Ahead of Threats Program At- A- Glance Wednesday, September 9

Event Check-In and Badge Pick-Up Welcome Address Keynote Address Plenary Sessions Poster Session

Thursday, September 10

Event Check-In Breakout Sessions (Biological, Chemical/Radiological) Plenary Session

Friday, September 11

Event Check-In Color Guard Ceremony Awards Ceremony Plenary Session Closing Keynote


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WEDNESDAY WEDNESDAY

2015


WEDNESDAY

LRN 2015: Staying Ahead of Threats Wednesday, September 9 8:00 a.m. - 9:00 a.m. Arrive at Centers for Disease Control and Prevention Campus 8:00 a.m. - 4:45 p.m. Event Check-In and Badge Pick-Up Tom Harkin Global Communications Center Lobby C.E.U.s and Objectives 4.25 contact hours for today’s sessions (588-833-15)At the conclusion of Day 1, the participant will be able to: ■■

Describe the evolving role of the LRN and articulate its past accomplishments and future vision.

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Discuss how the LRN supports public health.

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Describe partnerships, coordination and response efforts involved in international and domestic laboratory preparedness.

Welcome and Opening Panel Plenary Session Auditorium B1/B2/B3 Panel: 9:00 a.m. - 10:30a.m. Andrew C. Cannons, Ph.D., HCLD (ABB), Planning Committee Chair, Laboratory Director, Bureau of Public Health Laboratories – Tampa, Division of Disease Control and Health Protection, Florida Department of Health Elizabeth Franko, DrPH, Laboratory Director, Georgia Public Health Laboratory, Georgia Department of Public Health


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Brenda Fitzgerald, MD, Commissioner and State Health Officer, Georgia Department of Public Health Thomas Frieden, MD, MPH, Director, Centers for Disease Control and Prevention David Nabarro, MSc, BM BCh, MFPHM, FRCP, Special Representative to the United Nations Secretary–General 10:30 a.m. - 10:45 a.m.

Break Tom Harkin Global Communications Center Lobby

Future of the Laboratory Response Network Plenary Session Auditorium B1/B2/B3 Moderator: Jasmine Chaitram, MPH, MT (ASCP) Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention Panel: 10:45 a.m. – 11:05 a.m.

J oanne Andreadis, PhD, Senior Advisor for Laboratory Preparedness, Office of Public Health Preparedness and Response, Centers for Disease Control and Prevention

11:05 a.m. – 11:25 a.m.

J ames L. Pirkle, MD, PhD, Director, Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention

11:25 a.m. – 11:45 a.m. Julie Villanueva, PhD, Branch Chief, Laboratory Preparedness and Response Branch, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention 11:45 a.m. – 12:00 p.m. Questions/Answers

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10:00 a.m. – 5:00 p.m.

osters Available for Viewing P Tom Harkin Global Communications Center Lobby

12:00 p.m. - 1:30 p.m. Lunch Available for Purchase Tom Harkin Global Communications Center Lobby 12:30 p.m. - 1:30 p.m.

Poster Presenters Available for Discussion

International Response to Chemical Weapons Plenary Session Auditorium B1/B2/B3 Moderator: Rudolph Johnson, PhD, Laboratory Chief, Emergency Response Branch, Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention 1:30 p.m. - 2:00 p.m. International Response to Chemical Weapons Hugh Gregg, PhD, Head of Organisation for the Prohibition of Chemical Weapons Laboratory, Organisation for the Prohibition of Chemical Weapons 2:00 p.m. - 2:15 p.m.

Questions/Answers

2:15 p.m. – 2:30 p.m. Break Tom Harkin Global Communications Center Lobby FBI Partnerships to Respond to Threats Plenary Session Auditorium B1/B2/B3 Moderator: Nicholas Paquette, MS, Microbiologist, Hazardous Materials Science Response Unit, Federal Bureau of Investigation Laboratory 2:30 p.m. - 3:00 p.m. History of Powder Letters Sent via Mail Douglas Beecher, PhD, Science Lead, Chemical, Biological, Radiological, Nuclear Sciences Unit (CBRNSU), Federal Bureau of Investigation Laboratory


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3:00 p.m. - 3:20 p.m.

ig Data and Personal Health Information: B National & Transnational Security Implications Edward You, MS, Supervisory Special Agent, Weapons of Mass Destruction, Federal Bureau of Investigation

3:20 p.m. – 3:30 p.m.

Questions/Answers

3:30 p.m. – 3:45 p.m. Break Tom Harkin Global Communications Center Lobby 2014 Ebola Outbreak Response Plenary Session Auditorium B1/B2/B3 Moderator: Scott Hughes, PhD, Associate Director, Public Health Laboratory, New York City Department of Health and Mental Hygiene Panel: 3:45 p.m. - 4:05 p.m.

race Kubin, PhD, Director, Laboratory Services G Section, Texas Department of State Health Services

4:05 p.m. – 4:25 p.m.

eter Iwen, MS, PhD, D (ABMM), Director, P Nebraska Public Health Laboratory

4:25 p.m. – 4:45 p.m. Mark Wolcott, PhD, Director, Special Pathogens Laboratory, United States Army Medical Research Institute of Infectious Diseases 4:45 p.m. – 5:00 p.m.

Questions/Answers

5:00 p.m.

Adjourn Day 1

Note: When you exit CDC, please retain your meeting badge.

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THURSDAY


THURSDAY

2015

THURSDAY

Thursday, September 10 8:00 a.m. - 8:45 a.m. Arrive at Centers for Disease Control and Prevention Campus 8:00 a.m. - 5:00 p.m.

Event Check-In and Badge Pick-Up

C.E.U.s and Objectives 4.0 contact hours for today’s Biological Breakout session (588-834-15) At the conclusion of Day 2, the participant of the Biological Breakout session will be able to: ■■

Describe lessons learned from real cases and exercises.

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Describe new technologies and capabilities of the LRN for Biological Threats Preparedness (LRN-B) as well as initiatives for assay development.

4.0 contact hours for today’s Chemical Breakout session (588-835-15) At the conclusion of Day 2, the participant of the Chemical Breakout session will be able to: ■■

Describe lessons learned from real cases and exercises.

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Discuss the concept of the LRN for Radiological Threats Preparedness (LRN-R) and the importance of partnerships for preparedness and threat response.

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Describe how laboratories are involved in radiological preparedness activities.

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Describe new technologies and capabilities of the LRN for Chemical Threats Preparedness (LRN-C).


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1.5 contact hours for today’s General session (588-836-15) At the conclusion of Day 2, the participant of the General session will be able to: ■■

Outline biosafety and biosecurity practices as it relates to the select agent program.

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Discuss ways to implement effective biosafety and biosecurity programs within the laboratory.

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Describe the role of biosecurity for allhazard preparedness and response.

8:00 a.m. – 5:00 p.m. Posters Available for Viewing Tom Harkin Global Communications Center Lobby LRN-B IN ACTION BREAKOUT SESSION Auditorium B3 Moderator: Patricia Blevins, MPH, LRN Laboratory Coordinator, San Antonio Metro Health District Laboratory, City of San Antonio Metropolitan Health District 9:00 a.m. – 9:20 a.m. LRN in Action: Local, State and National Response to the October Texas Ebola Outbreak Erin Swaney, Team Leader, Biothreat Team and Emerging Preparedness, Laboratory Services Section, Texas Department of State Health Services 9:20 a.m. – 9:40 a.m. Multifaceted Response to a Large-Scale Brucella species Laboratory Exposure Megan Price, PhD, Bioterrorism Molecular Senior Scientist, Virginia Division of Consolidated Laboratory Services, Commonwealth of Virginia Department of General Services

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9:40 a.m. – 10:00 a.m. Testing for MERS-CoV, the Indiana Lab Story Judith Lovchik, PhD, D (ABMM), Assistant Commissioner, Laboratory Director, Indiana State Public Health Laboratory, Indiana State Department of Health 10:00 a.m. – 10:20 a.m. A Perfect Storm: LRN Laboratory Response to Simultaneous Plague & Tularemia Outbreaks During Challenging Circumstances Larry Sater, MS, Biological and Chemical Terrorism Response Coordinator, Security Officer, Laboratory Services Division, Colorado Department of Public Health & Environment 10:20 a.m. – 10:30 a.m. Questions/Answers LRN-C IN ACTION BREAKOUT SESSION Auditoriums B1/B2 Moderator: Amy D. Watson, PhD, LRN-C Program Coordinator, National Center for Environmental Health, Centers for Disease Control and Prevention 9:00 a.m. – 9:25 a.m. LRN-C: Beyond Preparedness, Increasing Roles and Expanding Partnerships Stefan Saravia, MPH, Chemical Threat Preparedness Coordinator, Minnesota Public Health Laboratory Division, Minnesota Department of Health 9:25 a.m. – 9:50 a.m. A Triangulation Strategy Between CT/Poison Control/Hazmat Jason Mihalic, Chemistry Office Chief, Arizona Bureau of State Laboratory Services, Arizona Department of Health Services 9:50 a.m. – 10:15 a.m. Unknown Substance Training for HAZMAT Responders: Assessment and Laboratory Sample Collection Meshel Mork, MS, Senior Chemist, Wisconsin State Laboratory of Hygiene, University of Madison-Wisconsin LRN 2015: Staying Ahead of Threats

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10:15 a.m. – 10:30 a.m. Questions/Answers 10:30 a.m- 10:45 a.m. Break Tom Harkin Global Communications Center Lobby LRN-B Unusual Case Presentations Breakout Session Auditorium B3 Moderator: William Nauschuetz, PhD, Laboratory Biopreparedness Manager, United State Army Medical Command 10:45 a.m. – 11:05 a.m. Response to an Unknown Pulmonary Illness Incident with an Unexpected Outcome LaToya Griffin-Thomas, PhD, MS, Bioterrorism Response Coordinator, Virginia Division of Consolidated Laboratory Services, Commonwealth of Virginia Department of General Services 11:05 a.m. – 11:25 a.m.

SAMRIID Ebola Response: Vaccine U Interactions and Canines William Dorman, Biothreat Coordinator, US Army Medical Research Institute of Infectious Diseases

11:25 a.m. – 11:45 a.m. Domestic Response to the First Ebola Case Daniel Serinaldi, MT (ASCP), Bioterrorism Response Coordinator, Dallas County Health and Human Services 11:45 a.m. – 12:00 p.m. Questions/Answers Radiological Preparedness and Response Breakout Session Auditoriums B1/B2 Moderator: David Saunders, PhD, Physicist, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention 10:45 a.m. – 11:05 a.m. Response to Nuclear Events-Lessons from Fukushima 30


Blaine Rhodes, MChE, Director, Office of Environmental Laboratory Sciences, Washington Public Health Laboratories, Washington State Department of Health 11:05 a.m. – 11:25 a.m. CDC Radiological Preparedness and Response Capabilities and the Potential for LRN for Radiological Preparedness Robert L. Jones, PhD, Chief, Inorganic and Analytical Toxicology Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention 11:25 a.m. – 11:45 a.m. Inorganic and Radiation Analytical Toxicology Branch (IRAT) Activities Deanna Jones, Research Chemist, Centers for Disease Control and Prevention 11:45 a.m. – 12:00 p.m. Questions/Answers 12:00 p.m. – 2:00 p.m. Lunch Off-Campus On Your Own Developing New Assays and Technologies for the LRN-B Breakout Session Auditorium B3 Moderator: Brad Bowzard, PhD, Acting Team Lead, Bioterrorism Rapid Response and Advanced Technology Laboratory, Laboratory Preparedness and Response Branch, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention 2:00 p.m. – 2:20 p.m. The development and use of a C. perfringens assay for use as a positive extraction control Michael Perry, MS, Laboratory Supervisor, New York State Department of Health, Wadsworth Center 2:20 p.m. – 2:40 p.m. Performance Evaluation of the EndoPep MS Assay for Detection of Botulinum Neurotoxins


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Susan Maslanka, PhD, Team Lead, National Botulism Laboratory, Centers for Disease Control and Prevention 2:40 p.m. – 3:00 p.m. Developing Variola Virus Specific qPCR Assays Yu, Li, PhD, Team Lead, Molecular Diagnostics, Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention 3:00 p.m. – 3:15 p.m.

Questions/Answers

Developing New Assays and Technologies for the LRN-C Breakout Session Auditorium B1/B2 Moderator: Thomas Blake, PhD, Research Chemist, Team Lead, Emergency Response Branch, National Center for Environmental Health, Centers for Disease Control and Prevention 2:00 p.m. – 3:15 p.m. Benefits of Switching to High-Throughput Specimen Analysis for a CT Laboratory Luke C. Short, PhD, Supervisory Chemist, District of Columbia Public Health Laboratory, DC Department of Forensic Sciences Development of Dichlorotyrosine as a Biomarker of Chlorine Exposure Brian Crow, PhD, Senior Method Development Scientist, Emergency Response Branch, National Center for Environmental Health, Centers for Disease Control and Prevention Methods Development toward the Detection of Soapberry Toxins in Human Urine Melissa Carter, PhD, Senior Method Development Scientist, Emergency Response Branch, National Center for Environmental Health, Centers for Disease Control and Prevention 32


Untargeted Data-Dependent Acquisition of Analytes from Human Blood Products Confirming Exposure to Organophosphorus Nerve Agents Thomas P. Matthews, PhD, Research Chemist, Emergency Response Branch, National Center for Environmental Health, Centers for Disease Control and Prevention 3:15 p.m. - 3:30 p.m. Break Tom Harkin Global Communications Center Lobby Biosafety and Biosecurity Plenary Session Auditorium B3 Video Feed to Auditoriums B1/B2 Moderator: Michael Shaw, PhD, Senior Advisor for Laboratory Science, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention 3:30 p.m. – 5:00 p.m. Biosecurity and Catastrophic Preparedness Patrick Rose, PhD, Director, Pandemic and Catastrophic Preparedness, National Association of County and City Health Officials Implementing an Effective Biosafety Program Michael Pentella, PhD, MS, D (ABMM), William A. Hinton State Laboratory Institute, Massachusetts Department of Health and Human Services Laboratory Bio-Risk Management Reynolds M. Salerno, PhD, Senior Manager, Biological Sciences and Technologies, Sandia National Laboratories Federal Select Agent Program Robbin S. Weyant, PhD, Director, Division of Select Agents and Toxins, Centers for Disease Control and Prevention


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5:00 p.m.

Adjourn Day 2

Note: When you exit CDC, please retain your meeting badge.

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FRIDAY

FRIDAY

2015


FRIDAY

Friday, September 11 8:00 a.m. - 8:45 a.m. Arrive at Centers for Disease Control and Prevention Campus 8:00 a.m. - 1:00 p.m.

Event Check-In and Badge Pick-Up

C.E.U.s and Objectives 1.5 contact hours for today’s sessions (588858-15) At the conclusion of Day 3, the participant will be able to: ■■

Describe some of the challenges associated with developing a state-wide response plan with first responders.

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Describe the importance of laboratory findings for law enforcement investigations.

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Discuss technologies that are currently being used by first responders as well as the development of new field-based technologies.

8:00 a.m. – 1:00 p.m. Posters Available for Viewing Tom Harkin Global Communications Center Lobby Color Guard Ceremony Auditorium B1/B2/B3 9:00 a.m. – 9:15 a.m.

Georgia State Defense Force

Essential Partnerships and Funding to Stay Ahead of Threats Plenary Session Auditorium B1/B2/B3 Moderator: Eric Blank, Dr.P.H., Senior Director, Public Health Systems, Association of Public Health Laboratories


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9:15 a.m. – 10:00 a.m. Partnerships to Enhance the LRN Scott J. Becker, MS, Executive Director, Association of Public Health Laboratories Importance of Federal Funding to Sustain the LRN Peter Kyriacopoulos, Senior Director, Public Policy, Association of Public Health Laboratories Awards Ceremony Auditorium B1/B2/B3

Presenters:

10:00 a.m. - 10:45 a.m. Judith Lovchik, PhD, D(ABMM), Assistant Commissioner, Laboratory Director, Indiana State Public Health Laboratory A. Christian Whelen, PhD, D(ABMM), Laboratory Director, Hawaii Department of Health State Laboratories 10:45 a.m. - 11:00 a.m. Break Tom Harkin Global Communications Center Lobby Partnering to Evaluate Field Devices and Respond to Threats Plenary Session Auditorium B1/B2/B3 Moderator: Noel Stanton, MS, Wisconsin State Laboratory of Hygiene, University of Madison-Wisconsin 11:00 a.m. - 12:30 p.m. Evaluation of the use of Field-Based PCR as a Screening Tool for First Responders Christina Egan, PhD, CBSP, Chief, Biodefense Laboratory, New York State Department of Health, Wadsworth Center Georgia’s Biological Threat Response Guidance for 1st Responders Daniel Polanski, Chemical, Biological, Radiological, Nuclear (CBRN) Coordinator, Georgia Department of Public Health 38


Stranger than Fiction: The Remarkable Saga of a Would-Be Terrorist in Northern Minnesota Maureen Sullivan, MPH, Emergency Preparedness Unit Supervisor, Minnesota Public Health Laboratory Division, Minnesota Department of Health Joint Biological Threat Response System: An All-Hazards Approach to Responding to Suspicious Substances Cheryl Gauthier, MA, MT (ASCP), Director, Bioterrorism Response Laboratory, William A. Hinton State Laboratory Institute, Massachusetts Department of Health and Human Services Closing Plenary Session Auditorium B1/B2/B3 12:30 p.m. – 1:00 p.m.

ndrew C. Cannons, Ph.D., HCLD (ABB), Planning A Committee Chair, Laboratory Director, Bureau of Public Health Laboratories – Tampa, Division of Disease Control and Health Protection, Florida Department of Health

1:00 p.m.

Adjourn 2015 LRN National Meeting


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2015


POSTERS

POSTERS

POSTERS

Poster Sessions Tom Harkin Global Communications Center Lobby To be displayed from Wednesday, September 9th at 10:00 a.m. to Friday, September 11th at 1:00 p.m. Poster presenters will be available for questions during lunch on Wednesday, September 9th from 12:30 p.m. – 1:30 p.m. 1. Chikungunya, a Vector Borne Emerging Threat Samantha Tostenson, Research Microbiologist, United States Army Medical Research Institute for Infectious Disease 2. Evaluation of the BacterioScanTM Instrument for Rapid Antimicrobial Susceptibility Testing of Yersinia pestis and Bacillus anthracis Julia Bugrysheva, PhD, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, Christine Lascols, MS, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, Linda Weigel, PhD, Team Lead, Centers for Disease Control and Prevention 3. The Design and Validation of Variola Virus Specific Diagnostic Assays A. Kondas, Victoria Olson, PhD, Team Lead, Poxvirus Team, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Yu, Li, PhD, Team Lead, Molecular Diagnostics, Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, J. Abel, K. Wilkins, Inger Damon, MD, PhD, Chief, Poxvirus Program, Captain, USPHS, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Jonathan Turner, MS, MB (ASCP), Poxvirus Program, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention


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4. Clandestine Laboratories: Beyond Recreational Pharmaceuticals New York State Department of Health First Responder Training Program Alan J. Antenucci, All-Hazards Training Coordinator, New York State Department of Health, Wadsworth Center, Biodefense Laboratory 5. Laboratory Response Network Chemical (LRN-C) Level 3 Resource Handbook Jennifer Jenner, PhD, Chemical Threat Response Laboratory Coordinator, Massachusetts Department of Public Health, Nicole Gethin, MS, Chemical Threat Response Laboratory Assistant Coordinator, Massachusetts Department of Public Health, Teresa Miller, Chemical Threat Coordinator, Michigan Department of Community Health 6. Comparison of DNA Extraction Methods for Whole Genome Sequencing of Bacillus anthracis Heather McLaughlin, PhD, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, Amy Gargis, PhD, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, Julia Bugrysheva, PhD, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, Andrew Carter, MPH, Microbiologist, IHRC Inc., Centers for Disease Control and Prevention, David Sue, PhD, Microbiologist, Centers for Disease Control and Prevention, Linda Weigel, PhD, Team Lead, Centers for Disease Control and Prevention 7. EXPRESS—Exercise of Preparedness and Response System Tina Fan, P.D, Research Scientist 1/Program Manager, Chemical Terrorism Laboratory, New Jersey Department of Health Public Health & Environmental Laboratories 8. Dallas County LRN: Ebola Response 2014 Daniel Serinaldi, MB (ASCP), LRN BT Coordinator, Dallas County Health and Human Services 9. Applications of Pyrosequencing Technology for Identification and Characterization of Burkholderia pseudomallei. Nelson Delgado, PhD, D(ABMM), RBP, Research Scientist-1, BioThreat Response Laboratory Coordinator, ARO, New Jersey Department of Health Public Health & Environmental Laboratories, A. MacMillan, S.

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DasGupta, H. Shah, Ondrea Shone, Research Scientist, New Jersey Department of Health Public Health & Environmental Laboratories, D. Galkowski 10. Laboratory Preparedness and Response to Ebola Virus in New York City Scott Hughes, PhD, Associate Director, Public Health Laboratory, New York City Department of Health and Mental Hygiene 11. Biothreat Environmental Sample Collection Training for First Responders: Highlighting Local, State and Federal Partnerships Mark Glazier, Director, Biological Preparedness, Laboratory Outreach, and Logistics, Indiana State Department of Health Laboratories 12. Analysis of Mercury in Urine by ICP-MS David Freund MT(AMT), Medical/Clinical Specialist, Georgia Public Health Laboratory, Stacey Gonder MPH, MLS(ASCP), Medical/Clinical Specialist, Georgia Public Health Laboratory, Noemi Kalath MPH, MLS(ASCP), Medical/Clinical Specialist, Georgia Public Health Laboratory, 13. Enhancing Rapid Electronic Laboratory Reporting: Collaborative Efforts and Progress with LRN-LIMSi Indira Srinivasan, PMP, IT Project Manager, Centers for Disease Control and Prevention, Emory Meeks, Branch Chief, Information Systems Branch,Division of Health Informatics and Surveillance, Center for Surveillance, Epidemiology, and Laboratory Services, Office of Public Health Scientific Services, Centers for Disease Control and Prevention (CDC), Jasmine Chaitram, MPH, MT(ASCP) Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infections, Jon Lipsky, MBA, PMP, Consultant, J Michael Consulting, Jason Scott, PMP, Project Manager, J Michael Consulting 14. Implementation of Homeland Security Exercise Evaluation Program (HSEEP) to Test Plans and Protocols in the Laboratory Graciela Malave, MT, MLS(ASCP) CM, BT & CT Coordinator, Biological and Chemical Emergencies Laboratory of the Puerto Rico Department of Health


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15. Comparative Study of a Lateral Flow Assay to the LRN Time-Resolved Fluorescence Assay for Screening of Ricin Toxin in Environmental Samples Michael Perry, MS, Laboratory Supervisor, New York State Department of Health, Wadsworth Center 16. Implementing MALDI-TOF in the Public Health Laboratory for C. botulinum Neurotoxin Detection Dominick Centurioni, MS, Research Scientist, New York State Department of Health, Wadsworth Center 17. LRN in the Community: Responding to Ebola Valerie Requenez, MLS(ASCP), BT Coordinator, Corpus Christi-Nueces County Public Health Department Laboratory, Rachel Rios, MT(ASCP), Clinical Microbiologist, Corpus Christi-Nueces County Public Health Department Laboratory, Donna Rosson, MPH, MT(ASCP), Public Health Administrator, Corpus Christi-Nueces County Public Health Department Laboratory 18. Ebola Planning: The State Perspective. Marissa Bloemke, LRN Molecular Biologist, Infectious Disease Section, Minnesota Public Health Laboratory Division 19. The Great Flood: A Real Life Game of “Whack-a-mole”. Jackie Mahon, LRN Molecular Biologist, Infectious Disease Section, Minnesota Public Health Laboratory Division 20. From Threat to Reality: Biological and Chemical Emergencies Laboratory Response to Chikungunya virus Gloriene González Ruiz, Biological and Chemical Emergencies Laboratory of the Puerto Rico Department of Health 21. All Hands on Deck: What Happens When There is Something in the Water Courtney Demontigny, MS, LRN Molecular Assay Coordinator, Minnesota Public Health Laboratory Division

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22. Leveraging the LRN: A Step Toward Implementing International Health Regulations (IHR) (2005) Tyler Wolford, MS, Specialist, LRN, Association of Public Health Laboratories


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ACRONYMS ACRONYMS

2015


ACRONYMS

Acronyms AAVLD American Association of Veterinary Laboratory Diagnosticians

DHS

Department of Homeland Security

DHS OHA

Department of Health and Human Services Office of Health Affairs

DHS S&T

Department of Health and Human Services Science and Technology Defense Laboratory Network

AHRF

Assessment of Health Risks with Feedback

AML

Area Medical Laboratory

APHIS

Animal and Plant Health Inspection Service

DLN

APHL

Association of Public Health Laboratories

DoD

Department of Defense

DoD GEIS

ASM

American Society for Microbiology

United States Department of Defense Global Emerging Infections Surveillance and Response System

ASTM

American Society for Testing and Materials

DOE

Department of Energy

BA

Bacillus anthracis

DOJ

Department of Justice

BAIT

Biological Agent Identification and Counterterrorism Training

DSL

Division of Laboratory Systems

BOTE

Bio-Response Operational Testing Exercise

BRRATL

Bioterrorism Rapid Response and Advanced Technology Laboratory

BSL

Biosafety Level

BTRA

Bioterrorism Risk Assessment

CAP

College of American Pathologists

CBCT

Confidence Building Competency Test

CBNR

Chemical, Biological, Nuclear, and Radiological

CBRNSU

Chemical Biological Radiological Nuclear Science Unit (FBI Laboratory)

DTRA

Defense Threat Reduction Agency

EDD

Electronic Data Deliverable

EPA

Environmental Protection Agency

ERCL

Emergency Response Chemical Laboratory

ERLN

Environmental Response Laboratory Network

EUA

Emergency Use Authorization

FBI

Federal Bureau of Investigation

FDA

Food and Drug Administration

FERN

Food Emergency Response Network

FSIS

Food Safety and Inspection Service

GC-MS

Gas chromatography-mass spectroscopy Hemoagglutinine and Neuroaminidase Influenza Virus

CDC

Centers for Disease Control and Prevention

H1N1

CLIA

Clinical Laboratory Improvement Amendments

HHA

Handheld Assay

CoC

Chain of Custody

HHS

Department of Health and Human Services

HMRT

Hazardous Materials Response Team (FBI field hazmat teams)

COOP

Continuity of Operations Plan

CRCPD

Conference of Radiation Control Program Directors

CRP

Critical Reagents Program

HMSRU

CST

Civil Support Team (U.S. Army National Guard)

Hazardous Materials Science Response Unit (FBI Laboratory)

HSEEP

Homeland Security Exercise and Evaluation Program

CWA

chemical warfare agents

DBPR

Division of Bioterrorism Preparedness and Response

DEOC

Director of the Emergency Operations Center (Federal)

IAWG

Interagency Working Group

IBRD

Interagency Biological Restoration Demonstration

ICLN

Integrated Consortium of Laboratory Networks


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IRA

Integrated Response Architecture

PHAA

Public Health Actionable Assays

ISO

ISO International Organization for Standardization

PHEP

Public Health Emergency Preparedness

ITCC

Information Technology Communication Committee

PHILIS

Portable High Throughput Integrated Laboratory Identification Systems

JBAIDS

Joint Biological Agent Identification and Diagnostic System

PHLIP

Public Health Laboratory Interoperability Project

JLC

Joint Leadership Council

PSAA

Public Safety Actionable Assays

PT

Proficiency Testing

JPM CBMS Joint Program Executive Office for Chemical and Biological Medical Systems LIMS/LIS

Laboratory Information (Management) System

LIMSi

Laboratory Information Systems Management integration

LLNL

Lawrence Livermore National Laboratory

LPX

Laboratory Preparedness Exercise

QA

Quality Assurance

QAPP

Quality Assurance Program Plan

REEF

Radiological Evidence Examination Facility

RT-PCR

Real Time Polymerase Chain Reaction

SAIC

Science Applications International Corporation

SAP

Select Agent Program Severe Acute Respiratory Syndrome

LRN

Laboratory Response Network

SARS

LRN-B

Laboratory Response Network for Biological Terrorism Preparedness

SOW

Statement of Work

STP

Scenarios and Threat Prioritization

Laboratory Response Network for Chemical Terrorism Preparedness

SVOC

semi volatile organic compounds

USAHA

United States Animal Health Association

LRN-C LRN-R

Laboratory Response Network for Radiological Terrorism Preparedness

MCC

Method Coordination Committee

USAMRIID U.S. Army Medical Research Institute for Infectious Diseases

MOU

Memorandum of Understanding

USDA

Department of Agriculture

MSDS

Material Safety Data Sheet

VSP

Validate Sampling Plan

NAHLN

National Animal Health Laboratory Network

WLA

Water Laboratory Alliance

NCEH

National Centers for Environmental Health (under CDC)

WMD

Weapons of Mass Destruction

WMDC

NCG

Network Coordinating Group

WMD Coordinator (FBI field office coordinator)

NELAC

National Environmental Laboratory Accreditation Conference

WMDD

Weapons of Mass Destruction Directorate

NGB

National Guard Bureau

NIOSH

National Institute for Occupational Safety and Health

NLTN

National Laboratory Training Network

NMRC

Naval Medical Research Center

NPDN

National Plant Diagnostic Network

NRC

Nuclear Regulatory Commission

OHA

Office of Health Affairs

OIG

Office of Inspector General

PCR

Polymerase Chain Reaction

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NOTES


NOTES

2015

NOTES

Notes


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Notes

CS257147-I