annual report - Life Sciences Pennsylvania

137 downloads 304 Views 4MB Size Report
In 2017, your association surpassed major growth milestones; brought new resources to Pennsylvania's life sciences commu
2 0 1 7 L I F E

S C I E N C E S

P E N N S Y LVA N I A

ANNUAL REPORT

2 0 1 7 ANNUAL REPORT

C O N N E C T. A D V O C AT E . A D VA N C E . L I F E S C I E N C E S P E N N S Y L VA N I A W W W. L I F E S C I E N C E S PA . O R G

TA B L E O F C O N T E N T S LETTER TO MEMBERS

4

S T R AT E G I C P R I O R I T I E S

6

LIFE SCIENCES CENTER

7

E C O N O M I C I M PA C T R E P O R T

8

ADVOCACY 9 PROGRAMS 13 PA R T N E R S 1 9 MEMBERSHIP 20 BOARD OF DIRECTORS

25

GOVERNANCE COMMITTEES

26

SPONSORS 27

2

3

A LETTER TO OUR MEMBERS C O N N E C T. A D V O C AT E . A D VA N C E .

VISION

In 2017, your association surpassed major

membership. When we take a deeper look

an addition to Life Sciences PA’s Summit

were funded at the same level as the prior

growth milestones; brought new resources

into the make-up of our membership, we

Series, designed to help new entrepreneurs

fiscal year. The R & D Tax Credit was again

Pennsylvania is considered the most attractive

to Pennsylvania’s life sciences community by

see that there has been growth among all

learn the strategies and techniques used by

supported at $55 million.

location in the United States for establishing

way of innovative programming; achieved

sectors and in multiple regions throughout

experienced and successful entrepreneurs.

significant legislative successes at both the

the state of Pennsylvania.

state and federal levels; and furthered our

a rise of companies and organizations

mission of providing membership services

with fewer than 10 employees creating

and facilitating strategic connections by

businesses in Pennsylvania and joining our

expanding our offices in Wayne, PA to

membership.

create @LSPA – The Life Sciences Center,

and entrepreneurs speaks to the health…

the newest member benefit available to all

and fragility…of the life sciences industry.

a life sciences organization by life sciences leaders within the U.S. and by those outside the U.S. seeking to establish U.S. operations.

MISSION

Life Sciences PA members.

Life Sciences Pennsylvania’s mission is to

have experienced another year of making

ensure Pennsylvania is the United States hub

connections, advocating on behalf of the

for the life sciences by creating a business and public policy environment which fosters life sciences growth and success.

industry and advancing the life sciences in Pennsylvania.

We also saw a statewide and national

more programs targeted to specific sectors

policy approach to the opioid issue.

of and

our

membership,

lasting

facilitating

connections,

unique

continuing

to

represent our membership on the state and

events in 2017, including our Annual Dinner,

your association with the same number of

where 1,200 guests convened to celebrate

employees.

of our industry; the Spring Social, which has

nearly 300 life sciences executives came

our achievements in 2017, a snapshot of

together for a series of relaxing evenings

the successes of our membership, and the

to meet new colleagues and reconnect with

steps we’ve taken forward as a community.

those familiar; the Holiday Mixer, where a

record

200+

industry

professionals

gathered at the new Life Sciences Center for networking over cocktails and hors d’oeuvres;

and

Stadium

Advice



the

first-ever

from

the

Start-Up All

Stars,

We will continue to work closely with our national trade association partners and with our legislative champions.

20 17

We continue the progression of our strategic priorities to ensure a supportive climate in Pennsylvania to support company formation

the successes and outstanding achievements

pictures, and graphics – to share with you

associations in the United States in terms of

membership dues by executing and designing

than ever, all while continuing to operate

opportunity; our C-level Dinners, where

puts us among the top life sciences trade

drug pricing remains real in both capitals.

We held 32 educational and networking

This report offers us the chance – in words,

than 750 organizations in 2017, which

Life Sciences PA made the most of your

federal levels, and recruiting more members

been rated Life Sciences PA’s top networking

Life Sciences PA membership grew to more

4

The rise of small businesses

We’ve made

meaningful progress, by all measures, and

The threat posed by bad policy concerning

We also saw

In our advocacy efforts in Harrisburg and Washington, we met the challenges and threats head-on with many successes.

We

watched a new administration take shape in D.C. and saw approval of many longnegotiated issues.

and

retention

in

the

Commonwealth;

facilitate partnerships to advance company formation, innovation, job creation and success in the industry; and provide valued services for Association members. Together, we thank you for your continued

The Pennsylvania state budget remained burdened with structural debt and many more requests for limited funds. Fortunately, our allies in the Life Sciences Green House

support. CHRISTOPHER P. MOLINEAUX PRESIDENT & CEO

and Ben Franklin Technology Partners and our

state-supported

research

institutions

5

S T R AT E G I C P R I O R I T I E S

THE LIFE SCIENCES CENTER T o further our mission of providing membership services and facilitating strategic connections,

and

we have expanded our offices in Wayne, PA

industry,

to create @LSPA – The Life Sciences Center for

small companies, research institutions and

Pennsylvania. Our new, 8,600 square-foot Center

funding organizations to advance company

offers our members:

Facilitate

1

Ensure a supportive business and public policy climate in Pennsylvania to support company formation and retention in the

2

among

partnerships entrepreneurs,

between large

formation, innovation, job creation and

Commonwealth.

success in the industry.

• Networking and educational events • Happy hours • Meeting space • Center-wide internet service

3

Promote and support strategic engagement between

the

Pennsylvania

life

sciences

industry and key industry stakeholders.

4

Support efforts to position Pennsylvania as a top location for life sciences business and opportunity through select communication

• Q uiet, secluded rooms for phone calls, videoconferences or teleconferences • Conference and training rooms

initiatives. The Center is the newest member benefit available to all LSPA members.

5

Provide valued services and access to costefficient resources for Association members to make informed decisions and grow their businesses.

6

7

ADVOCACY SUCCESSES IN 2017

E C O N O M I C I M PA C T O F T H E L I F E S C I E N C E S I N D U S T R Y

I

n September, Life Sciences PA and KPMG released the 2017 Pennsylvania Life Sciences Impact Report, showcasing the significant role of the Pennsylvania life

sciences in leading national research and innovation, and driving the state economy.

peer states—California, Indiana, Massachusetts, Michigan, New Jersey, New York

T

and North Carolina. The peer states were selected based on their high concentration

In Washington, we worked closely with our national partners to secure affirmative votes for the

of life sciences activity relative to the national economy and their focus on research,

user fee legislation that must be renewed every five years and affects every sector of our industry.

development, and innovation.

President Trump signed the legislation into law in August. We also have advocated for important

The report compared Pennsylvania’s life sciences industry with that of designated

he advocacy efforts of Life Sciences Pennsylvania saw many notable successes in 2017 at the state and federal levels.

changes to the Affordable Care Act. The repeal of the Independent Payment Advisory Board was

Below is a summary of the contribution of the life sciences industry to the Pennsylvania

passed by the U.S. House of Representatives. We continued the work on our number one federal

economy. The report was presented during the Life Sciences Future conference.

legislative priority – the full repeal of the Medical Device Tax. We applaud the vote to reform our national tax system, which will allow many of our members to devote more resources to research

KEY FINDINGS*

and development. In recognizing the valuable contribution that the National Institutes of Health (NIH) play in basic scientific research, we are working with our congressional delegation in

LI F E S CIE NC E S I N PE N N S Y LVA N I A

ATTR AC TING CA P I TA L

Over the past five years, the life sciences industry experienced

Pennsylvania secured $147 million in venture capital funding in 2016,

gains in research, testing, and medical laboratories but a decline in

ranking 13th nationally and citing a need for investment moving forward.

pharmaceutical manufacturing, leading to uneven growth. The life

The

than half of the establishments comprised of fewer than 10 employees.

in

life

sciences

2016,

and

industry

indirectly

directly created

employed an

112,000

230,000

jobs

Technology Partners, they were restored to 2016 levels. The valuable Research & Development

expenditures.

The

Tax Credit remained at $55 million. In the prior fiscal year, more than 30 member companies

additional

through

In comparison to peer states, Pennsylvania had the highest 2016

industry generated a total state economic output of $88.5 billion.

National Science Foundation (NSF) funding rate, and the secondand

National

Institutes

of

Health

(NIH)

business

purchases

and

household

at the Life Sciences Greenhouses remained intact. After a brief threatened cut to the Ben Franklin

people

R E S E ARCH E X C E L L E N C E

NSF

We saw slow, but positive work on the state budget in Harrisburg, PA. The funding for our allies

EC ONOMIC CONTRI BUTI ON

sciences industry continues to be small business oriented, with more

highest

securing more funding for this important agency.

were awarded $13.3 million in tax credits.

COMMONWEALTH SUPPORT

funding

life

Threats exist in this environment in both capitals. For example, an ill-advised drug pricing bill was

sciences industry in the form of a dedicated agency, incentive

voted out of a state senate committee in December. We are working with our member companies

The

per capita. In the past five years, Pennsylvania was among the top five states in patent contributions, receiving 4,317 patents.

Commonwealth

of

Pennsylvania

offers

support

to

the

programs, and specific appropriations for life sciences programs.

to defeat this legislation that would expose proprietary financial information to competitors.

A C ADE MI C C ON T R I B U T I ON Pennsylvania universities conferred 578 doctorate degrees, ranking

Visit www.lifesciencespa.org/advance to view the full report.

4th highest in the nation during 2015. The state had seven of the top 100

*Source: Pennsylvania Life Sciences Industry. Report prepared by KPMG.

universities, including two in the top 100 Biological Sciences Program.

JAN 8

members that their voices are the ones needed in these capitals.

September 2017.

2017 MEMBER MILESTONES Synergy Pharmaceuticals receives FDA approval of Trulance for chronic idiopathic constipation

While we remain vigilant and active in Harrisburg and Washington, D.C., we remind our

FDA approves Egalet’s tamper-resistant chronic pain medicine – Arymo ER C-II

FEB Amgen, Inc. receives FDA approval of Parsabiv for secondary hyperparathyroidism in adults with chronic kidney disease on hemodialysis

AstraZeneca receives FDA approval of Qtern for inadequately controlled type 2 diabetes

9

S TAT E P O L I C Y C O M M I T T E E

FEDERAL POLICY COMMITTEE

TIM SULLIVAN, GSK (CHAIR)

AMY REDL, SANOFI (CHAIR)

BRYAN LEWIS, KCAN/ACKC

JEREMY ALLEN, SPARK

JOE MCGOWAN, NOVARTIS

BILL ANDRESEN, PENN

GREG MONTANARO, DREXEL

GREG ARONIN, PARAGON

CARA MOON, EGALET

COURTNEY LEE ASHLEY, MERCK

RITA NORTON, AMERISOURCEBERGEN

DANIEL AMBURN, UCB DOM ARGENTO, MERCK MARTHA AUSTER, VERTEX CHRIS BECK, PENN MEDICINE

KATHRYN LAVRIHA, SANOFI WENDY LAZARUS, PFIZER CHARLES LEITGELB, BAYER TIMOTHY LYDEN, ELI LILLY

SAUL BEHAR, SCIENCE CENTER

TIMOTHY P. MCNULTY, CMU

BRENDAN BENNER, MDMA

CARA MOON, EGALET

MEL BILLINGSLEY, LSGPA

PATRICK NORTON, PENN MEDICINE

JULIE COHEN, JOHNSON & JOHNSON

MARK O’ROURKE, TAKEDA

MICHELLE CONSALVO, SHIRE

JOY RUSSELL, GENENTECH

LINDA DAVIS, JANSSEN BIOTECH

MATT RUTH, ALMAC

PATRICK DENTINGER, ABSORPTION SYSTEMS JULIE EDDY, AMERISOURCE BERGEN NEELY FRYE, NOVARTIS VITO GALLO, LEHIGH UNIVERSITY ETHAN HASBROUCK, BMS GABRIEL HOLDSMAN, BTG

ANDY SANDUSKY, ABBVIE BARBARA SCHILBERG, BIOADVANCE DAVI D SMITH, PEPPER HAMILTON

PAULA BURG, PFIZER CARLA CARTWRI GHT, JOHNSON & JOHNSON

JED PERRY, SHIRE JESSE PRICE, ELI LILLY

PATRICK COLLINS, CSL BEHRING

MATTHEW RUTH, ALMAC

TIM FENTON, THERMO FISHER SCIENTIFIC

STEPHEN SCANGO, ABBVIE

TONY GIBSON, PITT

JENNIFER EVANS STACEY, WISTAR

PETER GROLLMAN, CHOP

DEBBIE TEKAVEC, CMU

KRISTIN DINI HERNANDEZ, TEMPLE

PHIL THEVENET, GSK

GABE HOLDSMAN, BTG CHRIS KOVOLSKI, VILLANOVA

LIFE SCIENCES CAUCUS CO–CHAIRS O U R L E G I S L AT I V E C H A M P I O N S I N H A R R I S B U R G

MARY LEE WATTS, AACR

S EN. AND Y D I NNI M AN

S EN. B O B M ENS C H

(D-CHESTER)

(R-BERKS, BUCKS, MONTGOMERY)

R E P. TIM BR IG G S (D-MONTGOMERY)

R E P. WA R R E N K A M PF

R E P. M A R K LON G IE TTI

(R-CHESTER)

(D-MERCER)

R E P. SCOTT PE TR I (R-BUCKS)

2 0 1 7 P U B L I C A F FA I R S S E R I E S S P O N S O R S

PAUL WILLIAMS, BMS

JENNIFER EVANS STACEY, WISTAR DEBRA STARK, BIR KARLA WHITE, CSL BEHRING DAVI D WILSON, DREXEL

2017 MEMBER MILESTONES

MAR

EMD Serono/Pfizer receives FDA approval of Bavencio for Merkel cell carcinoma

10

Genentech receives FDA approval of Ocrevus for multiple sclerosis

APR Novartis receives FDA approval of Kisqali for breast cancer

Harrisburg University opens a new biotechnology master’s program

Paratek Pharmaceuticals expands operations in King of Prussia, PA

Radius Health receives FDA approval of Tymlos for postmenopausal women with osteoporosis at high risk for fracture

Teva Pharmaceuticals receives FDA approval of Austedo for chorea associated with Huntington’s disease and tardive dyskinesia

Novartis receives FDA approval of Rydapt for FLT3 positive acute myeloid leukemia and mastocytosis

11

PROGRAMS F

U.S CONGRESSIONAL ENGAGEMENT

rom our Signature events to the smallest Special Interest programs, Life Sciences Pennsylvania produces a variety of programs each

RARE DISEASE CAUCUS

W

year. LSPA programs provide attendees opportunities to connect and interact with colleagues and industry leaders while staying

ith potential patient pools so small, there is often a personal story behind these companies’ foundings. As we continue to learn more about rare diseases, we have come into contact with a host of brave and passionate people — individuals committed to

supporting research and development of new treatments and therapies for patients dealing with rare disease each and every day. This

abreast of the latest developments and hot topics in life sciences. During the 32 programs held in 2017, more than 4,000 individual attendees heard from world-renowned speakers, breakthrough researchers and investment pioneers. Life Sciences Pennsylvania continues to provide a forum for the life sciences community to stay connected and continue growing.

bi-partisan and bi-cameral caucus works to educate other legislators on the needs and challenges of the 1.2 million Pennsylvanians who have a rare disease. We have seen quick action in Harrisburg as State Representative Marcy Toepel’s bill creating a Rare Disease Advisory Council was signed by the Governor in the summer.

R E P R E S E N TAT I V E S DUANE MILNE, CHESTER

LYNDA CULVER, NORTHUMBERLAND, SNYDER

THOMAS MURT, MONTGOMERY, PHILADELPHIA

JOHN GALLOWAY, BUCKS

KRISTIN PHILLIPS-HILL, YORK

MARK LONGIETTI, MERCER STEPHEN MCCARTER, MONTGOMERY

CAMERA BARTOLOTTA, BEAVER, GREENE, WASHINGTON LISA BOSCOLA, LEHIGH, NORTHAMPTON

CURTIS SONNEY, ERIE

MICHELLE BROOKS, CRAWFORD, ERIE, MERCER, WARREN

MARCY TOEPEL, MONTGOMERY

JAKE CORMAN, CENTRE, JUNIATA, MIFFLIN

JUDY WARD, BLAIR

JAY COSTA, ALLEGHENY ANDY DINNIMAN, CHESTER PATRICK STEFANO, FAYETTE, SOMERSET, WESTMORELAND ROBERT TOMLINSON, BUCKS GENE YAW, BRADFORD, SULLIVAN, LYCOMING

2017 MEMBER MILESTONES

MAY

Sanofi receives FDA approval of Kevzara for active rheumatoid arthritis

12

FUTURE IN SEPTEMBER (SEE P. 17 FOR DETAILS)

S E N AT O R S

PAUL COSTA, ALLEGHENY

WARREN KAMPF, CHESTER

CELLICON VALLEY PANEL FROM LIFE SCIENCES

AstraZeneca receives FDA approval of Imfinzi for advanced or metastatic urothelial carcinoma

JUN Inovio Pharmaceuticals announces strides toward a breakthrough HIV vaccine

CSL Behring receives FDA approval of Haegarda for routine prophylaxis to prevent hereditary angioedema attacks

Pittsburgh Life Sciences Greenhouse and Helomics partner to launch a diagnostics and precision medicine incubator

Neuronetics, Inc. receives $15M in funding for Neurostar

Fibrocell announces development of gene therapy with transformative potential for patients with recessive dystrophic epidermolysis bullosa 13

ANNUAL DINNER I

n Pennsylvania, our industry is defined by individuals and leaders who work tirelessly toward one overriding goal: helping patients around the world by addressing unmet medical needs. Through this unwavering dedication, Pennsylvania continues to be a global leader across the life sciences

industry. Each year, more than 1,200 life science professionals gather for the Annual Dinner to celebrate the successes of the prior year and to honor visionary leaders of the past whose legacies guide our industry in Pennsylvania.

2017 PROGRAM OVERVIEW

32

2 0 1 7 AWA R D R E C I P I E N T S

88

PROGRAMS

SPEAKERS

1, 1 2 1

4, 150

C O M PA N I E S REPRESENTED

AT T E N D E E S

CLARKSTON CONSULTING SCHOLARSHIP ERIC MCELHINNY, UNIVERSITY OF PITTSBURGH

PATIENT IMPACT AWARD JEFFERSON HEALTH SYSTEM

DEAL OF THE YEAR AWARD ALLERGAN ACQUISITION OF VITAE PHARMACEUTICALS

PRESIDENT’S SERVICE AWARD CHARLES R. HUNTINGTON, JR., SENIOR VICE PRESIDENTINVESTMENT OFFICER, THE HUNTINGTON/KRAUS FINANCIAL GROUP, WELLS FARGO

EMERGING COMPANY OF THE YEAR AWARD GENOMIND FEDERAL OFFICIAL OF THE YEAR AWARD CONGRESSMAN TIM MURPHY (R-18), U.S. HOUSE OF REPRESENTATIVES

SCIENTIFIC ACHIEVEMENT AWARD JULIUS YOUNGNER, SC.D., AMERICAN DISTINGUISHED SERVICE PROFESSOR EMERITUS, UNIVERSITY OF PITTSBURGH’S SCHOOL OF MEDICINE

FRANK BALDINO BIOSCIENCES CEO OF THE YEAR AWARD BOB RADIE, PRESIDENT & CEO, EGALET CORPORATION

STATE OFFICIAL OF THE YEAR AWARD SENATOR BOB MENSCH (R-24), PENNSYLVANIA STATE SENATE

HUBERT J.P. SCHOEMAKER LEADERSHIP AWARD M. STEPHEN HEILMAN, M.D., PRESIDENT, VASCOR, INC.

2017 MEMBER MILESTONES

JUL

1,178 clinical trials active in Pennsylvania

14

Janssen receives FDA approval of Tremfya for moderate-to-severe plaque psoriasis

OraSure Technologies receives WHO prequalification of OraQuick HIV Self-Test

Complexa raises $62M in series C financing to test CXA-10 in two orphan drug disease proof of concept trials

VenatoRx receives $9.4M from CARB-X to develop a new class of antibiotic to combat multi-drug resistant bacteria

Cutanea releases new mobile app for acne patients – Facing Forward

15

SUMMIT SERIES The Life Sciences Pennsylvania Summit Series is a collection of high-quality programs that are uniquely designed for and marketed to a

L

specific section of the LSPA membership. The Summits feature prominent industry speakers highlighting timely content, while providing numerous opportunities for strategic connections.

ife Sciences Future was developed with Pennsylvania’s diverse life sciences industry in mind – pharma, biotech, medical device and diagnostics, healthcare IT, contract

research organizations, academic research institutions, and the investment community.

Medtech + Digital Health Summit July 12, 2017 The Wistar Institute Philadelphia, PA

LSPA’s first MedTech + Digital Health Summit was a half-day program designed specifically for senior leaders, regulatory and quality experts, entrepreneurs, and business development executives from MedTech + Digital Health organizations in PA and beyond. The Summit featured various panel discussions focused on topics like innovation and funding, strategic priorities of the FDA, digital health analytics, and CMS reimbursement.

The agenda is driven by Life Sciences Pennsylvania members to ensure the content is relevant, engaging and thought-provoking.

M A J O R K E Y N O T E S & PA N E L I S T S OPENING KEYNOTE

Supply Chain Summit October 25, 2017 The Desmond Hotel Malvern Malvern, PA

Attendees at the LSPA Supply Chain Summit learned the newest strategies for handling life sciences industry supply chain needs. The event covered the state of global transportation, virtual supply chain management, product and serialization data, and good supply practices. Featured presenters included Paul Testa, Group Vice President at Shire, and Michael Araten, President and CEO of K’NEX BRANDS.

Jonathan Epstein, M.D., Executive Vice Dean and CSO, University of Pennsylvania, Perelman School of Medicine

Advice from the All Stars November 14, 2017 @LSPA - The Life Sciences Center Wayne, PA

CRO & CMO Summit November 17, 2017 West Pharmaceuticals Services, Inc.

Nearly 100 attendees participated in the first ever StartUp Stadium – Advice from the All Stars, an event designed to provide new entrepreneurs with strategies for successful pitching and presentations, in preparation for the JP Morgan Healthcare Conference and other investor conferences. The event showcased the most promising and innovative emerging companies in Pennsylvania, and created opportunities to meet with experienced legal and financial advisors, and other successful entrepreneurs from the life sciences industry. The CRO & CMO Summit was a half-day program designed specifically for those planning and conducting clinical trials, and those seeking advice on how to effectively partner with companies within the life sciences industry.

Dario Altieri, M.D., President and CEO, The Wistar Institute; Director, The Wistar Institute Cancer Center; Robert and Penny Fox Distinguished Professor

FROM THE HEART OF THE CELLICON VALLEY Adrian (Ad) Rawcliffe, CFO, Adaptimmune Jeff Marrazzo, CEO, Spark Therapeutics

Jessica Imrie, Head of Strategy and Operations for Cell and Gene Therapy within Rare Diseases, GlaxoSmithKline Moderator: Ali Gorman, R.N., Health and Medical Reporter, 6ABC Action News PATIENT SPOTLIGHT Montel Williams, Investor and Patient Advocate Phillippe Deschamps, President & CEO, Helius Medical Technologies

19 C O M PA N Y P R E S E N TAT I O N S

319

50 SPEAKERS + PA N E L I S T S

O R G A N I Z AT I O N S

Felix Hsu, Senior Vice President, Head of US Business Unit, WuXi AppTec

Jeri Lake, Patient

Exton, PA

703

POSTER P R E S E N TAT I O N S

T O TA L AT T E N D E E S

FIRESIDE CHAT

Moderator: Adam Taicher, Partner, Navigate Start-Up Stadium –

36

12

12 REVERSE PITCHES

S TAT E S R E P R E S E N T E D + WA S H I N G T O N , D . C

24 RESEARCH INSTITUTIONS

2017 MEMBER MILESTONES

AUG

AbbVie receives FDA approval of Mavyret for treatment of chronic HCV genotype 1,2,3,4,5 or 6

16

Jazz Pharma receives FDA approval of Vyxeos for treatment of newly-diagnosed therapy-related AML or AML with myelodysplasiarelated changes

Pfizer receives FDA approval of Besponsa for treatment of relapsed or refractory B-cell precursor acute lymphoblastic leukemia

Helius Medical Technologies opens a new corporate facility in Newtown, PA

Absorption System opens CGMPcompliant testing facility for gene and cell therapy products

FDA approves first-ever T-cell cancer treatment—Kymriah— pioneered at CHOP and Penn, commercialized by Novartis

17

EXECUTIVE DINNERS

PA R T N E R S

Life Sciences Pennsylvania hosts C-Level dinners throughout the year, lending an exclusive opportunity to those serving in the capacity of Chief Executive Officer, Chief Scientific Officer, Chief Medical Officer, Chief Financial Officer, or head of R&D at a Life Sciences PA core member company, to network with their peers.

I N T E R N AT I O N A L PA R T N E R S ASSOBIOTEC ITALIA

Chief Scientific Officer Dinner July 20, 2017 St. Davids Golf Course Wayne, PA

Chief Financial Officer Dinner November 7, 2017 St. Davids Golf Course Wayne, PA

Chief Executive Officer Dinner November 28, 2017 Merion Golf Club Ardmore, PA

At the 2017 Chief Scientific Officer Dinner, Life Sciences PA members joined together for a relaxing evening to meet and reconnect with their colleagues, and hear a keynote presentation from guest speaker, Dr. David H. Ledbetter, Executive Vice President and Chief Scientific Officer, Geisinger. Dr. Ledbetter discussed Geisinger’s MyCode Community Health Initiative, a precision medicine project that involves enrolling patients at Geisinger locations in Pennsylvania and beyond, to store blood and other samples for use in research—particularly genetic research—by Geisinger and its collaborators.

INDO-US SCIENCE & TECHNOLOGY FORUM

LITHUANIAN BIOTECHNOLOGY ASSOCIATION

December 6, 2017 @LSPA - The Life

ONE NUCLEUS TAIWAN BIO INDUSTRY ORGANIZATION

N AT I O N A L PA R T N E R S

This event, offered to those serving in the capacity of Chief Financial Officer, Chief Executive Officer, and/or VP of finance, featured a night of networking, meeting new colleagues, and a discussion with guest speaker, Ketan Patel, M.D., Partner, F-Prime Capital Partners. Dr. Patel discussed recent investment and growth within the life sciences industry, the investment climate in today’s industry, and the nuances in investment culture between the Boston, San Francisco and Philadelphia regions.

Keynote speaker, Madeline Bell, President and CEO of Children’s Hospital of Philadelphia (CHOP), shared her insights and experiences in the life sciences industry during the 2017 Chief Executive Officer Dinner. She spoke to upcoming technologies at CHOP, the importance of strategic partnerships to CHOP’s future, and the ecosystem at CHOP that allows them to grow in the life sciences industry. The evening provided an opportunity to meet with new colleagues and network with other members.

R E G I O N A L PA R T N E R S

H O L I D AY N E T W O R K I N G E V E N T Holiday Mixer

KARNATAKA BIOTECHNOLOGY AND INFORMATION TECHNOLOGY SERVICES

ALLEGHENY CONFERENCE ON COMMUNITY DEVELOPMENT

GREATER PHILADELPHIA ALLIANCE FOR CAPITAL AND TECHNOLOGIES

PHILADELPHIA CONVENTION AND VISITORS BUREAU

BEN FRANKLIN TECHNOLOGY PARTNERS OF CENTRAL AND NORTHERN PENNSYLVANIA

HEALTHCARE INSTITUTE OF NEW JERSEY

PITTSBURGH LIFE SCIENCES GREENHOUSE

HERSHEY CENTER FOR APPLIED RESEARCH

PITTSBURGH TECHNOLOGY COUNCIL

BEN FRANKLIN TECHNOLOGY PARTNERS OF NORTHEASTERN PENNSYLVANIA

INNOVATION WORKS

SELECT GREATER PHILADELPHIA

LEHIGH VALLEY ECONOMIC DEVELOPMENT COUNCIL

THE CHAMBER OF COMMERCE FOR GREATER PHILADELPHIA

BIOADVANCE

LIFE SCIENCES GREENHOUSE OF CENTRAL PENNSYLVANIA

THE MAIN LINE CHAMBER OF COMMERCE

CHESTER COUNTY CHAMBER OF BUSINESS & INDUSTRY

NEW JERSEY BIO NEW JERSEY TECHNOLOGY COUNCIL

VALLEY FORGE CONVENTION AND TOURISM BOARD

PENNSYLVANIA BIOTECHNOLOGY CENTER OF BUCKS COUNTY

WORLD TRADE CENTER OF GREATER PHILADELPHIA

BEN FRANKLIN TECHNOLOGY PARTNERS OF SOUTHEASTERN PENNSYLVANIA

Before the holidays, Life Sciences PA had a chance to connect with the Board of Directors and new members in a festive setting during its annual Holiday Mixer. The informal mixer brought together LSPA members over cocktails and hors d’oeuvres.

Sciences Center

CHESTER COUNTY ECONOMIC DEVELOPMENT COUNCIL

Wayne, PA

DELAWARE BIO

UNIVERSITY CITY SCIENCE CENTER

2017 MEMBER MILESTONES

SEP

Bayer granted accelerates FDA approval on Aliqopa for treatment of follicular lymphoma

18

Genentech receives FDA approval of Actemra for CAR T-cell induced cytokine release syndrome

GlaxoSmithKline and Adaptimmune partner to advance and commercialize T-cell therapy program

Temple University and University of Pittsburgh selected by NIH as two of 11 clinical hubs nationwide

National Lacrosse League and Egalet Corporation announce education partnership to promote non-narcotic pain option and responsible pain management

CSL Behring presents Penn State University with a $4.92M gift to help transform biotech education and research

19

WELCOME 2017 NEW MEMBERS

MEMBERSHIP

I

n 2017, Life Sciences Pennsylvania experienced a recordbreaking year for membership growth, ending the year with

755 member organizations representing all sectors of the life sciences: biotech, pharma, devices, diagnostics, research,

755 MEMBER C O M PA N I E S

funding, digital health, contract research organizations, patient advocacy groups, and service providers. A deeper look into the membership composition shows growth among all sectors and in multiple regions throughout the state, as well as an increase in the number of organizations with fewer than 10 employees—a direct testament to both the vibrancy but fragility of the life sciences community. The increasing size and diversity of our membership puts Life Sciences PA among

135 NEW MEMBERS IN 2017

the top life sciences trade associations in the United States. While our membership continues to evolve, what has not changed is our commitment to creating a business and policy environment which fosters life sciences growth and success. This expanded network provides even greater opportunity to facilitate strategic connections among members and to advocate for effective public policy. Together, Life Sciences PA seeks to create an environment to ensure the Commonwealth is considered the most attractive location in the United States

1,393

MEMBERS CONNECTED I N L S PA P R I VAT E L I N K E D I N G R O U P

for establishing a life sciences organization.

2017 MEMBER MILESTONES

OCT 20

GlaxoSmithKline receives FDA approval of Shingrix for herpes zoster (shingles)

Pittsburgh Life Sciences Greenhouse awarded a grant for health information technology programs

Inovio Pharmaceuticals, Wistar Institute, the University of Penn, and GeneOne Life Sciences team up to tackle Zika

Harmony Biosciences raises $270M and acquires exclusive US rights to develop and market pitolisant, a narcolepsy drug from Bioproject

Strongbridge BioPharma raises $23.4M. Proceeds will support development and expansion of several experimental and approved treatments

3FX ACADEMY OF NOTRE DAME DE NAMUR ACCURA TECHTONIQ LLC A D VA N C E D R P O ALEXANDERWERK, INC. ALLERGAN, INC. A M Y L O I D O S I S F O U N D AT I O N APO TECHNOLOGIES, INC. ARCWEB TECHNOLOGIES ARIEL PRECISION MEDICINE AZER SCIENTIFIC AZZUR GROUP LLC B A K E R T I L LY BEACON HILL PHARMA BLINK CONSULTING B O TA N I X P H A R M A C E U T I C A L S L T D . BOUNDARY MEDICAL B R I D G E I N N O VAT I O N S B U C H A N A N P U B L I C R E L AT I O N S C A L I B E R A S S O C I AT E S CANCER GENETICS, INC. CAPGENIC ADVISORS CAREER CONCEPTS, INC. DBA CCI CONSULTING CAREFORM CARMA THERAPEUTICS LLC CBM GROUP CENERO CENTER CITY FILM & VIDEO CFGI CIRCADIANCE CIVI BIOPHARMA, INC. CONRAD O’BRIEN, PC CONSEGNA PHARMA COOK MYOSITE, INC. COOLEY LLP C O U R A G E G R O W T H PA R T N E R S C U R I N G R E T I N A L B L I N D N E S S F O U N D AT I O N DECHERT LLP DREAMIT VENTURES E . M . M . A . I N T E R N AT I O N A L C O N S U L T I N G G R O U P EDSPIRE ELEVEN BIOTHERAPEUTICS, INC. EXCALIVIR, INC. E Y WA P H A R M A FIVE RIVERS RX

Aevi Genomic Medicine announces a $28M private stock placement led by CHOP. The CHOP Foundation will provide an additional $5M in equity financing

F M C O S T C O N TA I N M E N T L L C F R E S H S TA R T C A R E E R S FRIEDMAN LLP FRONTIDA BIOPHARM, INC. FULTON BANK GEMINI ADVISORS GO2 HARMONY BIOSCIENCES HCP CONCIERGE, LLC H E A L T H C A R E R O YA L T Y PA R T N E R S HELIUS MEDICAL TECHNOLOGIES HUMOTECH IMMUNOMET THERAPEUTICS, INC. I M VA X I N D U S T R Y S TA N D A R D R E S E A R C H I N T R AV E N T M E D I C A L PA R T N E R S , L P J.N. SOLUTIONS LLC JPG HEALTHCARE LLC L . E . A . F. P H A R M A C E U T I C A L S L L C L AW L E Y LIPELLA PHARMACEUTICALS, INC. LOCKTON, CO. L U M I S C O R P. L Y O P H I L I Z AT I O N T E C H N O L O G Y, I N C . MARKITECTS, INC. MASTERCONTROL, INC. MAZARS USA, INC. MEDNET SOLUTIONS MEKHOS HEALTH LLC MIKAN GROUP MJ WOODDELL LLC MOBILION SYSTEMS M V M L I F E S C I E N C E PA R T N E R S L L P NAMSA N AT I O N A L ATA X I A F O U N D AT I O N N AT I O N A L O S T E O P O R O S I S F O U N D AT I O N N E O V I TA B I O P H A R M N E P H C U R E K I D N E Y I N T E R N AT I O N A L F O U N D AT I O N NEURORX, INC. NMS LABS NOBLE LIFE SCIENCES, INC. ONCORA MEDICAL, INC. ONSPIRA THERAPEUTICS, INC. OPTINOSE OPTUM LIFE SCIENCES O R T H O - TA G

Optinose closes $138M stock offering. Money raised will support launch and development efforts for Xhance for treatment of nasal polyps in adults

PA B R E A S T C A N C E R C O A L I T I O N PENDULUM CLINICAL DEVELOPMENT C O N S U L TA N T S , L L C PHARMALEX DEVELOPMENT SERVICES, LLC P R O L I FA G E N L L C PSIOXUS THERAPEUTICS PUBLICIS HEALTH PULMONESCENCE DIAGNOSTICS Q U A N T I TAT I V E R A D I O L O G Y S O L U T I O N S QUANTUS, INC. QUARTESIAN QUEBEC TRADE OFFICE IN PHILADELPHIA RECENSA THERAPEUTICS R E C T O R C O M M U N I C AT I O N S , I N C . R E N E R VA , L L C RUBITECTION SCIENCE HISTORY INSTITUTE SD MEDED, INC. S FA T H E R A P E U T I C S SICK CELLS SIMON’S FUND S L V E R N I C K C O M M U N I C AT I O N S SMARTCPR SMITHWISE SPRINGER LEADERSHIP STYERGROUP SUAZIO CONSULTING SUNOVION PHARMACEUTICALS, INC. TA K E D A P H A R M A C E U T I C A L S U S A , I N C . TA L E E B I O T H E B A N D I S H G R O U P, L L C T H E R A P E U T I C A R T I C U L AT I O N S L L C THERMAQUIL, INC. TMUNITY THERAPEUTICS, INC. T R O V I TA H E A L T H S C I E N C E TUNNELL CONSULTING VA L L E Y F O R G E T O U R I S M & C O N V E N T I O N B O A R D V I L L A N O VA U N I V E R S I T Y V I R PA X P H A R M A C E U T I C A L S , I N C . W E S T E R N PA C H A P T E R , N AT I O N A L H E M O P H I L I A F O U N D AT I O N W H C & A S S O C I AT E S WITHUMSMITH+BROWN WIZSOLUTION LLC WUXI APPTEC, INC. YOUR GENERAL COUNSEL LLC

Arbutus Biopharma corporation & Gritstone Oncology sign licensing deal for personalized cancer immunotherapies

US FDA approves new easy-to-use, once-weekly BYDUREON BCISE injectable medicine for patients with type 2 diabetes

21

DIAMOND MEMBERS

MEMBERSHIP GROWTH OVER TIME

BioPharm Devices

BioPharm Insight

MEMBERSHIP 800 600

604

651

674

755

716

547

504 432

400 346

308

378

LEADERSHIP MEMBERS

200

2007

2008

2009

2010

2011

2012

MEMBERSHIP BY SECTOR

2013

2014

2015

2017

C O R E & A S S O C I AT E M E M B E R S

6%

39%

40%

755

11%

2016

2017

20 1 7

60%

40%

biotechnology or pharmaceutical research and development, drug discovery, medical device

3%

2%

development, and contract 15% 4%

5%

14%

7%

L I BERTY P R O P ERTY TR U ST

BALLAR D SPAHR LLP

DU A NE MO R R I S L L P

L I L LY U SA , L L C

BR I STOL-MYE R S SQU I BB C OMPANY

E R NST & Y O U NG , L L P

MO R G A N, L EW I S & BO CKI U S L L P

C E LE R I ON, I NC .

F I SH ER SCI ENTI FI C

MO R P HO TEK, I NC.

C ONNE R STR ONG & BU C KE LE W

I R OK O P HA R MA CEU TI CA L S, L L C

P ECO , A N EX EL O N CO MPA NY

KPMG L L P

P EP P ER HA MI LTO N L L P

TA KED A P HA R MA CEU TI CA L S, U SA , I NC. TEL EFL EX I NCO R P O R ATED THE SA R I A N G R O U P AT HI G HTO W ER W U X I A P P TEC, I NC.

to the life sciences industry. Core: Organizations involved in

12%

DSM BI O MED I CA L

consulting and business services

13%

716

ALMAC GR OU P

Associate: Businesses providing

7%

14%

2016

research organizations involved

5%

in preclinical research.

2%

1%

BIO T ECH 1 5 %

B I OT E CH 14%

AS S O C IAT E 3 0 2 COR E 4 5 3

S E RV I C E ORGANI Z ATI ON 39%

FUNDING 2 %

S E R V I CE OR GAN I ZAT I ON 40%

F UN DI N G 3%

C RO 7%

MEDICA L DEVICE 1 2 %

C R O 5%

M E DI CAL DE V I CE 11%

PAT IEN T AD V OC AC Y 4%

PHA RMA 1 4 %

PAT I E N T ADV OCACY 5%

PHAR M A 13%

D IG ITAL H EALTH 1%

RESEA RCH / UNIVERSIT Y 6 %

D I GI TAL HE ALT H 2%

R E S E AR CH / UN I V E R S I T Y 7%

MEDICAL DEVICE & DIAGNOSTICS COMMITTEE BR U C E SHOOK, I NTAC T VASC U LAR (C HAI R ) DAVI D ANDE R SON, ORTE Q NE I L C AMPBE LL, MOSAI GE N ADAM DAKI N, PLE XU S

TOM HESS, G ENO MI ND GAB E HO L D SMA N, BTG

CHR I STI A N MA ND ER S, P R O METHEA N L I FE SCI ENCES

LI AM KEL LY, TEL EFL EX

CHR I STO P HER MO L I NEA U X , L I FE SCI ENCES P ENNSY LVA NI A

MAR C MA L A ND R O , I NNO VATI O N I NSTI TU TE

JO HN SCHU EL ER , FU JI R EBI O

R O N SPA I R , O R A SU R E ER I C TEU TSCH, D SM BI O MED I CA L A L A N W EST, P I TTSBU R G H L I FE SCI ENCES G R EEN HO U SE

D I G I TA L H E A L T H C O M M I T T E E MU KHTAR AHME D (C HAI R ), BI OC LI NI C A

JASO N FR ED ER I CK, ER NST & YOUNG

MAR I A F OR E R O, R I DGE TOP HE ALTH

DAV I D L I ND SAY, O NCO R A MED I CA L

FR A NK MI NEL L A , PA I NQ X O O D AY E SHU KL A , HV H PATI ENT P R ECI SI O N A NA LY TI CS

THO MA S W O L SKI , THE W EBB L AW FI R M

2017 MEMBER MILESTONES

NOV

Genentech, Inc. receives FDA approval of Hemlibra for prevention or reduction of bleeding episodes in patients with hemophilia A

22

Merck receives FDA approval of Prevymis for cytomegalovirus following allogenic hematopoietic stem cell transplant

Genisphere LLC raises $7M to advance its 3DNA nanotechnology platform designed to improve targeted drug delivery

Brandywine & Drexel break ground on Schuylkill Yards – a $3.5B project

Onconova Therapeutics raises $1.4M to focus on late-stage clinical testing of lead drug candidate, IV Rigosertib, for myelodysplastic syndromes

FDA approves Genentech’s HEMLIBRA (emicizumabkxwh) for hemophilia A with inhibitors

Recro Pharma announces $100M financing deal managed by Athyrium Capital management. Funds will support a milestone for IV meloxicam for moderate-to-severe pain

CIC partners with University City Science Center & Venture Café in Philadelphia Innovation Center

23

S AV I N G M I L L I O N S F O R M E M B E R S

2017 BOARD OF DIRECTORS

T

ARMANDO ANIDO Chairman of the Board & Chief Executive Officer Zynerba Pharmaceuticals

he Life Sciences Pennsylvania SAVE Program (Service, Access, Value and Ease) is a powerful group purchasing program offering discounts on products and services to LSPA members. This program enables members to grow and expand their current operations, while saving capital and

ERIN BRUBAKER Vice President, R&D Strategy Development GlaxoSmithKline Pharmaceuticals

resources. In 2017, our members saved more than $8.4 million by utilizing our member services program.

BioPharm Devices

M E M B E R S AV I N G S , GROUP PURCHASING

BioPharm Insight

CHRISTOPHER BURNS, PH.D. President & Chief Scientific Officer VenatoRx Pharmaceuticals CHRISTOPHER CASHMAN President & Chief Executive Officer Marinus Pharmaceuticals

10

$8.4M

BRIAN DOERNER Partner Ballard Spahr LLP

8

$6.5M Savings (in millions)

6

the sarian group

JAMES DATIN President & Chief Executive Officer BioAgilytix

MATTHEW GANTZ Chief Executive Officer OxThera

$5.2M

MAXINE GOWEN, PH.D. President & Chief Executive Officer Travena, Inc.

$4.5M

NINA GUSSACK Partner Pepper Hamilton LLP

4

BRIAN HALAK, PH.D. Partner Domain Associates GABRIEL HOLDSMAN General Counsel US, Senior Vice President, Legal Operation BTG International Inc.

2

0

2014

2015

2016

2017

JOHN HUBBARD, PH.D., FCP President & Chief Executive Officer BioClinica, Inc.

JOSEPH LA BARGE Head of Business Administration & General Counsel Spark Therapeutics, Inc.

JULIAN RITCHEY US Head Vaccine Public Affairs and Advocacy Sanofi Pasteur

MAHMOOD LADHA Head of US Business Operations AstraZeneca Pharmaceuticals

JOHN RYAN President & Chief Executive Officer Unilife Corporation

DAVID LEDBETTER, PH.D. FACMG Executive Vice President & Chief Scientific Officer Geisinger Health System

KATHLEEN SHAY Partner Duane Morris LLP

TERRI LEE TAYLOR Vice President, State Government Affairs & Policy Merck & Co., Inc. JEFFREY LIBSON Partner Cooley, LLP MARC MALANDRO, PH.D., CLP, RTTP Vice President of Operations, Science Chan Zuckerberg Initiative CHRISTIAN MANDERS Chief Operating Officer Promethean LifeSciences VINCENT MILANO Chief Executive Officer Idera Pharmaceuticals, Inc. CHRISTOPHER MOLINEAUX President & Chief Executive Officer Life Sciences Pennsylvania RITA NORTON Senior Vice President Government Affairs & Public Policy AmerisourceBergen Corporation ROBERT RADIE President & Chief Executive Officer Egalet, Inc.

ERIC TEUTSCH President DSM Biomedical STEPHEN TULLMAN Managing Partner NeXeption NEAL WALKER, D.O. President & Chief Executive Officer Aclaris Therapeutics

BRUCE SHOOK President & Chief Executive Officer Intact Vascular, Inc.

BRYAN WOLF, M.D., PH.D. Executive Vice President & Chief Scientific Officer The Children’s Hospital of Philadelphia

STEPHEN SIMPSON Partner Growth Markets Life Sciences Ernst & Young, LLP

STEPHEN YODER, M.D., MBA Head, Specialty Pharmaceuticals Search & Evaluation Business Development Bristol-Myers Squibb

ROBERT SMITH Senior Vice President, Global Gene Therapy Business Rare Disease Pfizer Innovative Health Pfizer Inc. RONALD SPAIR Chief Operating Officer & Chief Financial Officer OraSure Technologies, Inc. JENNIFER STRONG Partner KPMG LLP JOHN SWARTLEY, PH.D., MBA Associate Vice Provost & Managing Director Penn Center for Innovation University of Pennsylvania PAUL TESTA Group Vice President Head of Supply Chain Shire Pharmaceuticals

THANK YOU TO OUR FORMER BOARD MEMBERS FOR YOUR CONTRIBUTIONS.

S TEP HEN ALLAN NEI L C AMP BELL GLEN GAULTO N MI C HAEL HO ERRES P HI LI P HO S BAC H DENNI S J AC KMAN BRI AN MC VEI GH J O HN SC HUELER P ERRY S TERNBERG ALAN W ES T MI C HAEL YANG

2017 MEMBER MILESTONES

DEC

Aclaris Therapeutics receives FDA approval of Eskata for seborrheic keratoses

24

Merck receives FDA approval of Steglatro for type 2 diabetes mellitus

Sunovian receives FDA approval for Lonhala Magnair Inhalation Solution to treat COPD

Lia flushable pregnancy test receives FDA approval

LifeX launches in Pittsburgh

Takeda and TiGenix announce Cx601 (darvadstrocel) received positive CHMP opinion to treat complex perianal fistulas in Crohn’s disease

Spark Therapeutics, Inc. receives FDA approval for novel gene therapy – Luxturna for rare form of inherited vision loss

25

GOVERNANCE COMMITTEES ADVOCACY GABRIEL HOLDSMAN CHAIR

IN RECOGNITION OF OUR GENEROUS SPONSORS We are deeply appreciative of the following individuals for their generous support in bringing you the 2017 Annual Report. ARMANDO ANIDO

DAVID LEDBETTER, PH.D., FACMG

STEPHEN SIMPSON

Zynerba Pharmaceuticals

Geisinger

Ernst & Young, LLP

CHRISTOPHER BURNS, PH.D.

TERRI LEE TAYLOR

ROBERT SMITH

VenatoRx Pharmaceuticals

Merck & Co., Inc.

Pfizer Inc.

CHRISTOPHER CASHMAN

JEFFREY LIBSON

RONALD SPAIR

Marinus Pharmaceuticals

Cooley, LLP

OraSure Technologies, Inc.

BRUCE SHOOK

JAMES DATIN

MARC MALANDRO, PH.D., CLP, RTTP

JENNIFER STRONG

RONALD SPAIR

BioAgilytix Labs

University of Pittsburgh

KPMG LLP

BRIAN DOERNER

CHRISTIAN MANDERS

PERRY STERNBERG

Ballard Spahr LLP

Promethean LifeSciences

Shire Pharmaceuticals

MAXINE GOWEN, PH.D.

BRIAN MCVEIGH

JOHN SWARTLEY, PH.D., MBA

Trevena, Inc.

GlaxoSmithKline Pharmaceuticals

University of Pennsylvania

NINA GUSSACK

VINCENT MILANO

ERIC TEUTSCH

Pepper Hamilton LLP

Idera Pharmaceuticals, Inc.

DSM Biomedical

BRIAN HALAK, PH.D.

RITA NORTON

STEPHEN TULLMAN

Domain Associates

AmerisourceBergen Corporation

NeXeption

GABRIEL HOLDSMAN

ROBERT RADIE

NEAL WALKER, D.O.

BTG International Inc.

Egalet, Inc.

Aclaris Therapeutics

JOHN HUBBARD, PH.D., FCP

JULIAN RITCHEY

BRYAN WOLF, M.D., PH.D.

BioClinica, Inc.

Sanofi Pasteur

Children’s Hospital of Philadelphia

JOSEPH LA BARGE

KATHLEEN SHAY

STEPHEN YODER, M.D. MBA

Spark Therapeutics, Inc.

Duane Morris, LLP

Bristol-Myers Squibb

MAHMOOD LADHA

BRUCE SHOOK

AstraZeneca Pharmaceuticals

Intact Vascular, Inc.

DENNIS JACKMAN TERRI LEE TAYLOR BRIAN MCVEIGH CHRISTOPHER MOLINEAUX JULIAN RITCHEY KATHLEEN SHAY

EXECUTIVE MARC MALANDRO, PH.D., CLP CHAIR MAXINE GOWEN BRIAN HALAK JEFFR EY LIBSON VINCENT MILANO CHRISTOPHER MOLINEAUX STEPHEN TULLMAN

AUDIT VINCENT MILANO - CHAIR THOMAS HESS JEFFR EY LIBSON EDMUND LYNCH CHRISTOPHER MOLINEAUX STEPHEN SIMPSON STEPHEN TULLMAN STEPHEN WEBSTE R

26

27

6 5 0

E A S T

S U I T E

S W E D E S F O R D

R O A D

1 9 0

WAY N E ,

PA

1 9 0 8 7

WWW.LIFESCIENCESPA.ORG