Jul 31, 2012 - natural history of SCAD, its associations and optimal treatment. ...... Suh SY, Kim JW, Choi CU, Kim EJ,
DOI: 10.1161/CIRCULATIONAHA.112.105718
Clinical Features, Management and Prognosis of Spontaneous Coronary Artery Dissection
Running title: Tweet et al.; Spontaneous coronary artery dissection
Downloaded from http://circ.ahajournals.org/ by guest on October 20, 2017
Marysia S. Tweet, MD1; Sharonne N. Hayes, MD1; Sridevi R. Pitta, MBBS1; Robert D. Simari, MD1; Amir Lerman, MD1; Ryan J. Lennon, MS2; Bernard J. Gersh, MB, ChB, DPhil1; Sherezade Khambatta, DO3; Patricia J.M J.M. M. Best, Best st,, MD1; Charanjit S. Rihal, MD, MBA1; Rajiv Gulati, MD, PhD1
1
Division Di ivision ooff Ca Cardiovascular ard rdio iovvasc vasccul ula lar ar D Diseases; isea is ease ea ses; se s 2Di s; Division ivi visi s on of si of Biomedical Biiom omed edic ed i al Statistics ic Sta tati t sti ti ticcs and nd Informatics, Inf nfor orma or mati ma tics ti cs,, Mayo cs Ma C Cl Clinic, in nic ic,, Rochester, Rooch hessteer,, MN; MN; 3S St. t. John John nP Providence rovvid videnc ncee He nc H Health alth hS System, ystem, m D m, Detroit, ettro roit, MI M MI;;
Correspondence: Rajiv Gulati, MD, PhD Division of Cardiovascular Diseases Mayo Clinic 200 First Street SW Rochester, MN 55905 Phone: 507-538-6325 Fax : 507-255-2550 E-mail:
[email protected] Journal Subject Codes: [3] Acute coronary syndromes; [4] Acute myocardial infarction; [24] Catheter-based coronary interventions: stents; [48] Carotid and Vertebral A. Dissection; [97] Other Vascular biology 1
DOI: 10.1161/CIRCULATIONAHA.112.105718
Abstract:
Background - Spontaneous coronary artery dissection (SCAD) is an acute coronary event of uncertain etiology. Clinical features and prognosis remain insufficiently characterized. Methods and Results - A retrospective single-center cohort study identified 87 patients with angiographically confirmed SCAD. Incidence, clinical characteristics, treatment modalities, inhospital outcomes and long-term risk of SCAD recurrence or major adverse cardiac events (MACE) were evaluated. Mean age was 42.6 years and 82% were female. Extreme exertion at Downloaded from http://circ.ahajournals.org/ by guest on October 20, 2017
SCAD onset was more frequent in males (7/16 vs 2/71, p
