Almustansiriya medical college , medical college ... Al Mustansiriya. Al Mustansiriya Medical College , ...... San Diego, CA: Amylin Pharmaceuticals, Inc. 2009. 2.
Incretin--Based Therapies for the Incretin Treatment of Type 2 Diabetes: Update on the Benefits and Risks Dr. Abdulameer Abdullah AlAl-Ashbal Ass.Prof. ; Consultant Diabetologist Almustansiriya medical college , Department of Medicine ; Alyermouk Teaching Hospital
Dr. Abdulameer Al Al--Ashbal Consultant Diabetologist; Ass. Professor of Medicine Al Mustansiriya Medical College , Department of Medicine ; Alyermouk Teaching Hospital
My disclosure : No financial relationships with any commercial interests
Very important note Almost all the references mentioned by this lecture which deal with incretin hormones and benefits of subsequent incretin-based drugs are sponsored or supported by drugs manufactures While almost all the references which deal with adverse effects and particularly serious ones are not sponsored or supported by drugs manufactures
The gastrointestinal tract has a crucial role in the control of
energy homeostasis through its role in
the digestion, absorption, and assimilation of ingested nutrients. Dr. Abdulameer Abdullah Al- Ashbal ; Ass.Prof. , Consultant Diabetologist
The role of
Insulin in
glucose homeostasis is a firmly established concept and forms the cornerstone of discussions of the pathophysiolgy of diabetes.
Dr. Abdulameer Abdullah Al- Ashbal ; Ass.Prof. , Consultant Diabetologist
However, how glucose enters the blood stream has profound effects on magnitude of stimulatory effect of
glucose on insulin secretion Dr. Abdulameer Abdullah Al- Ashbal ; Ass.Prof. , Consultant Diabetologist
The observation that in response to hyperglycemic stimuli, oral glucose elicits a greater insulin response than
intravenous glucose, is termed , which accounts for up to 60% of postprandial insulin release in healthy people
The observation that in response to hyperglycemic stimuli, oral glucose elicits a greater insulin response than
intravenous glucose, is termed
“The Incretin Effect “ , which accounts for up to 60% of postprandial insulin release in healthy people
The observation that in response to hyperglycemic stimuli, oral glucose elicits a greater insulin response than
intravenous glucose, is termed
“The Incretin Effect “ , which accounts for up to 60 60% % of postprandial insulin release in healthy people
The incretin effect Energy administration via The gut The parenteral route
Glucose (Insulin secretagogue)
Insulin release
Glucose (Insulin secretagogue)
Insulin release
The incretin effect Energy administration via The gut The parenteral route
Glucose
(Insulin secretagogue)
Glucose (Insulin secretagogue)
Gut--derived signals Gut (Potent insulin secretagogues)
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Almustansiriya medical college , medical college ... Al Mustansiriya. Al Mustansiriya Medical College , ...... San Diego, CA: Amylin Pharmaceuticals, Inc. 2009. 2.
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