Hazardous Drug Inventory

Hazardous Drug Inventory

Universal (Green) - handling and disposed of using normal precautions. Low (Yellow) - handle at all times with gloves and appropriate engineering controls. Moderate (Orange) -handle at all times with gloves, gown, eye and face protection (with splash potential) and appropirate engineering controls. Dispensed/Common Drug Name (Formulation) and (NIOSH CATEGORY #)

Other Drug Name

Tablet

Hazardous Toxicity

Handling only No alteration

Contained Crush/Split

Minimum PPE Required

Minimum PPE required Low

abacavir (susp) (2) abacavir (tablet) (2) acitretin (capsule) (3)

ziagen/epzicom/trizivir ziagen/epzicom/trizivir soriatane

genotoxic/carcinogenic genotoxic/carcinogenic teratgogenic/reproductive

Low Universal

anastrazole (tablet) (1) android (capsule) (3) apomorphine (inj sq) (2) astagraf XL (capsule) (2) avordart (capsule) (3) azathioprine (tablet) (2) bicalutamide (tablet) (1) brisdelle (capsule) (3) caprelsa (tablet) (1) carbamazepine (suspension) (2)

arimidex methyltestosterone

antineoplastic teratogenic/reproductive

apomorphine tacrolimus dutasteride

genotoxic carcinogenic/teratogenic teratogenic/reproductive

apomorphine casodex

carcinogenic antineoplastic

paroxetine vandetanib

teratogenic/reproductive antineoplastic

Low Universal Moderate Universal Universal Universal Low Universal Low

tegretol

teratgogenic/carcinogenic

Low

carbamazepine (tablet) (2)

tegretol

teratgogenic/carcinogenic

Universal

carbamazepine ER (tablet) (2)

carbatrol/equatrol

teratgogenic/carcinogenic

Universal

clonazepam (tablet) (3) clonazepam ODT (tablet) (3) colchicine (capsule) (3) colcrys (tablet) (3) crizotinib (capsule) (1) cyclophosphamide (capsule) (1) cyclophosphamide (tablet) (1) cyclosporin (solution) (2)

Klonopin Klonopin colchicine colchicine xalkori cyclophosphamide cyclophosphamide

teratogenic/reproductive teratogenic/reproductive teratogenic/reproductive teratogenic/reproductive antineoplastic antineoplastic antineoplastic

Universal Universal Universal Universal Low Low Low

sandimmune/neoral /gengraf sandimmune/neoral /gengraf restasis cytotec

carcinogenic

depakote depakote er depakote sprinkles ulipristal

teratogenic/reproductive teratogenic/reproductive teratogenic/reproductive teratogenic/reproductive

cyclosporine (capsule) (2) cyclosporine (eye drops) (2) diclofenac/misoprostol (tablet) (3) divalproex (tablet) (2) divalproex ER (tablet) (2) divalproex sprinkle (capsule) (2) ella (tablet) (3)

Minimum PPE Required

carcinogenic carcinogenic teratogenic/reproductive

High (Red) - double gloves, gown, eye and face protection in addition to any necessary engineering controls. Open Capsule

Crush/Split Minimum PPE Minimum PPE required required Moderate

Universal

Moderate Moderate

High Moderate do not open Moderate

Low Moderate

Moderate High Moderate

do not split/crush Low

Moderate

do not split/ crush Low Moderate do not split/ crush Moderate Low

Moderate do not open High

Moderate

High

Low Universal Low Universal Universal Universal Universal Universal

Moderate Low Moderate do not split/ crush do not split/ crush Moderate Low

Moderate

Additional Information

Inventory (for facility QA)

Minimum PPE Required

emcyt (capsule) (1) estradiol (tablet) (2) estradiol (transdermal) (2) estrogen, conjugated (cream) (2) estrogen, conjugated (tablet) (2) estrogen/progesterone (patch) (2) estropipate (tablet) (2) etoposide (capsule) (1) exemestane (tablet) (1) fareston (tablet) (1) ferriprox (tablet) (2) fluconazole (injectable) (3) fluconazole (tablet) (3) fluorouracil (cream/solution) (1)

estramustine

antineoplastic

estradiol estradiol premarin premarin, prem-pro climara, combipatch ogen toposar aromasin toremifene deferiprone

carcinogenic/teratogenic carcinogenic/teratogenic carcinogenic/teratogenic carcinogenic/teratogenic carcinogenic/teratogenic carcinogenic/teratogenic antineoplastic antineoplastic antineoplastic teratogenic teratogenic/reproductive

diflucan

Low Universal Low Low Universal Low Universal Low Low Low Universal

High Low

Moderate

do not split/ crush Low

Moderate

Moderate Moderate Low

High High Moderate

High

only if reproductive risk - if not, universal

High

antineoplastic

fluoxymesterone (tablet) (2)

diflucan adrucil/carac/efudex /fluoroplex fluoxymesterone

carcinogenic/teratogenic

Universal

flutamide (capsule) (1) fosphenytoin (Inj-IM) (2) fosphenytoin (Inj-IV) (2) ganciclovir (Inj) (2)

flutamide cerebyx cerebyx cytovene

antineoplastic teratogenic teratogenic carcinogenic/teratogenic

Low Moderate High

geodon (injection) (3) gilenya (capsule) (2)

ziprasidone fingolimod

reproductive carcinogenic/teratogenic

Moderate

gleevac (tablet) (1) hexalen (capsule) (1) hydroxyurea (capsule) (1) icatibant (syringe/sq) (3)

imatinib altretamine droxia/hydrea firazyr

antineoplastic antineoplastic antineoplastic teratogenic/reproductive

Low Low Low

jalyn (capsule) (3) lamuvudine/zidovudine (tablet) (2) leflunomide (tablet) (2)

dutasteride/tamsulosin combivir arava

teratogenic/reproductive carcinogenic carcinogenic/teratogenic

Universal Universal Universal

do not split/ crush

letairis (tablet) (3) letrozole (tablet) (1) leukeran (tablet) (1) leuprolide (injection) (1)

ambrisentan

teratogenic/reproductive

do not split/crush

femara chlorambucil

antineoplastic antineoplastic

lupron depot/eligard/ lupaneta gleostine mitotane procarbazine

antineoplastic

provera megace megace alkeran purinethol purinethol

carcinogenic/teratogenic antineoplastic antineoplastic antineoplastic antineoplastic antineoplastic

Universal Low Low Moderate/ High (syringe/vial) Low Low Low Universal Moderate Low Low Moderate Low

lomustine (capsule) (1) lysodren (tablet) (1) matulane (capsule) (1) medroxyprogesterone (tablet) (2) megestrol (susp) (1) megestrol (tablet) (1) melphalan (tablet) (1) mercaptopurine (susp) (1) mercaptopurine (tablet) (1)

teratogenic/reproductive

antineoplastic antineoplastic antineoplastic

Universal

Low

Moderate

Moderate

chemo rated gloves Low

Moderate High

High

Universal

Moderate do not split/crush High High only if reproductive risk - if not, universal

Moderate Moderate Low

Moderate Moderate

Moderate

High High

High do not split/crush High Low

Moderate

Moderate Moderate

High High

Moderate

High

methotrexate (tablet) (1) methylergonovine (tablet) (3) multaq (tablet) (3) mycophenolate (tablet) (2) mycophenolic acid (pwd/recon) (2) myleran (tablet) (1) nevirapine (tablet) (2) nevirapine ER (tablet) (2) nevirapine Susp (tablet) (2) nexavar (tablet) (1) oxcarbazepine (susp) (2) oxcarbazepine (tablet) (2) oxcarbazepine ER (tablet) (2) panretin (topical) (3) paroxetine (tablet) (3) paxil (suspension) (3) paxil CR (tablet) (3) phenoxybenzamine (capsule) (2) phenytoin (suspension) (2) phenytoin (tablet) (2) phenytoin ER (capsule) (2) progesterone (capsule) (2) progesterone (intravaginal) (2) propylthiouracil (tablet) (2)

rheumatrex methylergonovine dronedarone

antineoplastic reproductive teratogenic/reproductive

cellcept mycophenolic acid busulfan

carcinogenic/teratogenic carcinogenic/teratogenic antineoplastic

viramune viramune XR viramune sorafenib

carcinogenic carcinogenic carcinogenic antineoplastic

trileptal trileptal oxtellar XR alitretinoin

carcinogenic carcinogenic carcinogenic teratogenic/reproductive

paxil/pexeva paroxetine paroxetine dibenzyline

teratogenic/reproductive teratogenic/reproductive teratogenic/reproductive carcinogenic

dilantin dilantin dilantin/phenytek prometrium first progest propylthiouracil

carcinogenic/teratogenic carcinogenic/teratogenic carcinogenic/teratogenic carcinogenic carcinogenic carcinogenic/teratogenic

propylthiouracil (tablet) (2)

propecia/proscar

qudexy XR (capsule) (3) raloxifene (tablet) (2)

Low Universal Universal Universal Moderate Low Universal Universal Low Low Low Universal Universal Low Universal Low Universal Universal Low Universal Universal Universal Low

Moderate High Low Moderate Low Moderate do not split/ crush Moderate High Low Moderate do not split/ crush Moderate

High

Low Moderate do not split/ crush Low

Moderate

do not crush/split moderate Low

Moderate do not open do not open

Universal

Low

Moderate

carcinogenic/teratogenic

Universal

Low

Moderate

topiramate evista

teratogenic/reproductive carcinogenic/teratogenic

Universal

rapamune (solution) (2)

sirolimus

carcinogenic/teratogenic

Low

rebetol (solution) (3) revlimid (capsule) (2) ribavirin (capsule) (3)

ribavirin lenalidomide

teratogenic/reproductive teratogenic

Low Universal

do not open

Universal

do not open

ribasphere/moderiba/ copegus/rebetol

teratogenic/reproductive

ribavirin (tablet) (3) risperdal (solution) (2) risperdal consta (injection) (2) risperdal M (dissolve tablet) (2) risperidone (tablet) (2) sabril (pwd packet) (3) sabril (tablet) (3) sirolimus (tablet) (2)

risperidone risperidone risperidone risperdal vigabatrin vigabatrin rapamune

teratogenic teratogenic teratogenic teratogenic teratogenic/reproductive teratogenic/reproductive carcinogenic/teratogenic

spironolactone (tablet) (2) sprycel (tablet) (1) sutent (capsule) (1)

aldactone dasatinib sunitinib

carcinogenic antineoplastic

Universal

Universal Low Moderate Universal Universal Moderate Universal Universal Universal Low Low

Moderate do not split/ crush

do not crush/split

do not split/ crush Low

Moderate

Low

Moderate

do not split/ crush Low Moderate do not split/crush High

tabloid (tablet) (1) tacrolimus (capsule) (2) tacrolimus (topical) (2) tamoxifen (tablet) (1) tarceva (tablet) (1) targretin (capsule) (1) targretin (gel) (1) tasigna (capsule) (1) temodar (capsule) (1) testosterone (inj- IM) (3) testosterone (transdermal- all forms) (3)

thioguanine

antineoplastic

prograf protoptic nolvadex/soltamox erlotinib bexarotene bexarotene nilotinib

carcinogenic/teratogenic carcinogenic/teratogenic antineoplastic antineoplastic antineoplastic antineoplastic antineoplastic

temozolomide testosterone

antineoplastic teratogenic/reproductive

striant/testim/androgel androderm/fortesta methyltestosterone

teratogenic/reproductive

Low Universal Low Low Low Low Moderate Low Low

valganciclovir (tablet) (2)

valcyte

teratpgenic/carcinogenic

Universal

valproic acid (capsule) (3) valproic acid (syrup) (3) victoza (Inj) (2)

depakene depakane liraglutide recombinant

teratogenic/reproductive teratogenic/reproductive carcinogenic/teratogenic

Universal Low

voriconazole (IV) (3)

vfend

teratogenic/reproductive

High

voriconazole (tablet) (3) votrient (tablet) (1) warfarin (tablet) (3) xeloda (tablet) (1) zelboraf (tablet) (1) zidovudine (capsule) (2) zidovudine (solution) (2) zidovudine (tablet) (2) ziprasidone (capsule) (3) zirgan (Eye Gel) (2)

vfend pazopanib

teratogenic/reproductive antineoplastic

coumadin capecitabine vemurafenib retrovir retrovir retrovir

teratogenic antineoplastic antineoplastic carcinogenic carcinogenic carcinogenic

geodon ganciclovir

reproductive carcinogenic/teratogenic

Universal Low Universal Low Low Universal Low Universal Universal

vorinostat

antineoplastic

zonegran abiraterone

teratogenic/reproductive antineoplasstic

zolinza (capsule) (1) zonisamide (capsule) (3) zytiga (tablet) (1)

Moderate Moderate Moderate

High High High chemo rated gloves High High only if reproductive risk - if not, universal

Low

retin-A/renova/ topiramate valganciclovir

topamax topamax hycamtin bosentan

High

Moderate

teratogenic/reproductive teratogenic/reproductive teratogenic/reproductive antineoplastic teratogenic/reproductive teratogenic/reproductive teratogenic/reproductive teratpgenic/carcinogenic

testred (capsule) (3) topiramate (tablet) (3) topiramate sprinkle (capsule) (3) topotecan (capsule) (1) Tracleer (tablet) (3) tretinoin (gel/cream) (3) tronkendi XR (capsule) (3) valcyte (sol - reconstitute) (2)

Moderate

Universal Universal Universal Low Universal Low Universal

Moderate Low

Moderate Moderate do not open

do not split/crush do not open

Moderate do not split/ crush Moderate

Moderate only if reproductive risk - if not, universal

Low Moderate do not split/crush Low Moderate Moderate High do not split/crush Moderate Low

Moderate Moderate

Low Low Universal Low

High Moderate do not split/crush