martin Levitt, David Warr, Louise Yelle, Harry L. Rayner, Wycliffe S. Lofters, ... M. Stern, Bo Yang, Patrick J. Flynn,
Jane and Louise Wilson #9781841660271 #84 pages #ellipsis, 2000 #2000 #Jeremy Millar, Jane Wilson, Claire Doherty Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity, to gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of 3 genome-wide association studies (GWAS) and 2 independent data sets genotyped on the Immunochip, including 10,588 cases and 22,806 controls. We identified. Volume and functional outcome of intracerebral hemorrhage according to oral anticoagulant type, objective: To compare intracerebral hemorrhage (ICH) volume and clinical outcome of non-vitamin K oral anticoagulants (NOAC)-associated ICH to warfarin-associated ICH. Methods: In this multicenter cross-sectional observational study of patients with anticoagulant. Development and validation of a brief screening instrument for psychosocial risk associated with genetic testing: a pan-Canadian cohort study, objectives To develop a brief, reliable and valid instrument to screen psychosocial risk among those who are undergoing genetic testing for Adult-Onset Hereditary Disease (AOHD). Design A prospective two-phase cohort study. Setting 5 genetic testing centres. Allele-specific HLA loss and immune escape in lung cancer evolution, immune evasion is a hallmark of cancer. Losing the ability to present neoantigens through human leukocyte antigen (HLA) loss may facilitate immune evasion. However, the polymorphic nature of the locus has precluded accurate HLA copy-number analysis. Here. Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study, background Men with germline breast cancer 1, early onset (BRCA1) or breast cancer 2, early onset (BRCA2) gene mutations have a higher risk of developing prostate cancer (PCa) than noncarriers. IMPACT (Identification of Men with a genetic predisposition to ProstAte. Cancer-related patient education: an overview of the last decade of evaluation and research, the soul moves under intense paraphrase. Diagnostic value of exome and whole genome sequencing in craniosynostosis, background Craniosynostosis, the premature fusion of one or more cranial sutures, occurs in∼ 1 in 2250 births, either in isolation or as part of a syndrome. Mutations in at least 57 genes have been associated with craniosynostosis, but only a minority of these are included. Outer & inner space: Pipilotti Rist, Shirin Neshat, Jane & Louise Wilson, and the history of video art, published to coincide with Outer & inner space: a video exhibition in three parts, organized by the Virginia Museum of Fine Arts. Part one (19 Jan-17 Mar 2002) consists of the video installation by Pipilotti Rist, Sip My Ocean, part two (6 Apr-2 June 2002) the video installation. Genetic heterogeneity in Cornelia de Lange syndrome (CdLS) and CdLS-like phenotypes with observed and predicted levels of mosaicism, background Cornelia de Lange syndrome (CdLS) is a multisystem disorder with distinctive facial appearance, intellectual disability and growth failure as prominent features. Most individuals with typical CdLS have de novo heterozygous loss-of-function mutations. Identification of amino acid residues in CD81 critical for interaction with hepatitis C virus envelope glycoprotein E2, human CD81 has been previously identified as the putative receptor for the hepatitis C virus envelope glycoprotein E2. The large extracellular loop (LEL) of human CD81 differs in four amino acid residues from that of the African green monkey (AGM), which does not bind. Patientâ reported outcomes in the ProtecT randomized trial of clinically localized prostate cancer treatments: study design, and baseline urinary, bowel and sexual, objectives To present the baseline patientâ reported outcome measures (PROM s) in the Prostate Testing for Cancer and Treatment (ProtecT) randomized trial comparing active monitoring, radical prostatectomy and externalâ beam conformal radiotherapy for localized. Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with, purpose: Preclinical data support a key role for the PI3K pathway in estrogen receptor-positive breast cancer and suggest that combining PI3K inhibitors with endocrine therapy may overcome resistance. This preoperative window study assessed whether adding. Prespecified dose-response analysis for a very early rehabilitation trial (AVERT, objective: Our prespecified dose-response analyses of A Very Early Rehabilitation Trial (AVERT) aim to provide practical guidance for clinicians on the timing, frequency, and amount of mobilization following acute stroke. Methods: Eligible patients were aged≥. Molecular mimicry in the decoding of translational stop signals, molecular mimicry was a concept that was revived as we understood more about the ligands that bound to the active center of the ribosome, and the characteristics of the active center itself. It has been particularly useful for the termination phase of protein synthesis, because. A study of the clinical and radiological features in a cohort of 93 patients with a COL2A1 mutation causing spondyloepiphyseal dysplasia congenita or a related, type 2 collagen disorders encompass a diverse group of skeletal dysplasias that are commonly associated with orthopedic, ocular, and hearing problems. However, the frequency of many clinical features has never been determined. We retrospectively. Whole-genome sequence-based analysis of thyroid function, normal thyroid function is essential for health, but its genetic architecture remains poorly understood. Here, for the heritable thyroid traits thyrotropin (TSH) and free thyroxine (FT4), we analyse whole-genome sequence data from the UK10K project (N= 2,287). Using. Ondansetron compared with dexamethasone and metoclopramide as antiemetics in the chemotherapy of breast cancer with cyclophosphamide, methotrexate, and, martin Levitt, David Warr, Louise Yelle, Harry L. Rayner, Wycliffe S. Lofters, Danielle J. Perrault, Kenneth S. Wilson, Jean Latreille. 13. Jane T. Hickok, Joseph A. Roscoe, Gary R. Morrow, Robert M. Stern, Bo Yang, Patrick J. Flynn, Harry E. Hynes, Jeffrey J. Kirshner, Richard. Jane and Louise Wilson, page 1. JANE AND LOUISE WILSON BORN 1967 Great Britain They live and work in London. EDUCATION 1996 Deutscher Akademischer Austauschdienst Berliner Kunstlerprogramm (Jane and Louise) 1993 Barclays Young Artist Award. 1999-2000 Turner Prize, Tate Gallery, London. What clinicians want: Findings from a psychotherapy practice research network survey, practice research networks may be one way of advancing knowledge translation and exchange (KTE) in psychotherapy. In this study, we document this process by first asking clinicians what they want from psychotherapy research. Eighty-two psychotherapists. Association analysis identifies 65 new breast cancer risk loci, breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast cancer risk remains unknown. Here we report the results of a genome. by KK McCaughan, DJ Scarlett, DN Wilson
