NLEM Final.pmd - ministry of health and sports

The Republic of The Union of Myanmar Ministry of Health and Sports Department of Medical Services

National List of Essential Medicines

(NLEM)

2016

Section 25

Sub Section - ၂၀၁၆

Myanmar Essential Medicines Project

CONTENTS No.

Description

1. 2. 3. 4. 5.

Foreword ……………………………………........... .... Acknowledgement …………………………........ .... Executive Summary ……………………….............. Significant features of NLEM (2016) ………....... Applications for review and revision of NLEM (2010)…………………………………....................... List of medicines in NLEM (2016) by therapeutic areas………………………………........................... Sections…………………………………………............. Section-1 Anaesthetics………………………........ Section-2 Analgesics, antipyretics, non-steroidal anti-inflammatory medicines (NSAIMs), medicines used to treat gout and disease modifying agents in rheumatoid disorders (DMARDs)… Section-3 Anti- allergics and medicines used in anaphylaxis…………………........... Section-4 Antidotes and other substances used in poisoning………………......... Section-5 Medicines for central nervous system…………………………………….... Section-6 Anti-infective medicines…………….. Section-7 Antimigraine medicines…………...... Section-8 Medicines affecting the blood……...

6. 7.

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Description Section-9 Section-10 Section-11 Section-12 Section-13 Section-14 Section-15 Section-16 Section-17 Section-18

Section-19 Section-20 Section-21 Section-22 Section-23

Section-24 Section-25 NLEM Myanmar 2016

Blood products and plasma substitutes………….........…………… Cardiovascular medicines………... Dermatological medicines (topical)……………....…………………. Diagnostic agents…………………... Disinfectants and antiseptics…… Diuretics….…………………………….. Gastrointestinal medicines…….. Hormones, other endocrine medicines and contraceptives… Immunologicals….………………….. Muscle relaxants (peripherally acting) and anticholinesterase inhibitors……………....………………. Ophthalmological preparation … Oxytocics and myometrial relaxants…………………………………….. Psychotherapeutic medicines…. Medicines acting on the respiratory tract…………….......... Solution correcting water, electrolytes and acid base balance………..…………………………. Vitamins and minerals………....... Medicines Used in Cancer Chemotherapy ......................

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Description Section-26 Otorhinolaryngological preparation Section-27 Medicines for urological system Annexes 1. Total items (486) in NLEM (2016)……... 2. Adding items (183) to year (2010) book 3. Deleting items (38) from year (2010) book…............................................. 4. Total items by category……………….......

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FOREWORD Essential Medicines are those that satisfy the priority health care needs of the population and these medicines are intended to be available within the context of functioning health systems at all times in adequate amounts, in the appropriate dosage forms, with assured quality, adequate information, at a price the individual and the community can afford. To follow the concepts of essential medicines and rational use of medicines, Myanmar Essential Medicines Project developed Standard Treatment Guideline for Basic Health Staff and National List of Essential Medicines (NLEM). Myanmar Essential Medicines Project has been implementing in collaboration with WHO since 1988. There are five categories of medicines in NLEM (2016) which are based on the professional level of health care providers. NLEM (2016) is the result of detailed revision by many experts such as professors from related fields, state and regional health directors, and programme managers.

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The new edition of National List of Essential Medicines (2016) contains (486) items and it can be used as supportive tool not only for procurement but also for good prescribing practices.

Professor Myint Han Director General Department of Medical Services

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ACKNOWLEDGEMENT 1. NLEM Task Force Committee 2. External Consultant 3. Professor and heads, Professors 4. State and Regional Health Directors 5. Programme Managers 6. Medical Superintendents The Task Force Committee for review and revision of NLEM (2010) wishes to record its heartfelt appreciation to external consultant, Dr. Pisonthi Chongtrakul, all the professor and heads, clinicians, state and regional health directors, programme managers and directors of hospitals, medical superintendents for the very effective suggestions and comments, WHO for financial support in revision process, senior officials from Ministry of Health & Sports for leadership role, financial for publication support and whoever involved in the development of this NLEM (2016). NLEM Myanmar 2016

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EXECUTIVE SUMMARY The National List of Essential Medicines (NLEM) is now becoming very important not only for procurement but also for health care providers to do as a reference which level should use what kind of medicines in the health system. A limited range of carefully selected essential medicines leads to better health care, better drug management, and lower costs. Essential medicines are those that satisfy the priority health care needs of the population and intended to be available within the context of functioning health systems at all times, in adequate amounts, in the appropriate dosage forms, with assured quality, and at a price the individual and the community can afford. Revision of NLEM was based the four important documents such as National List of Essential and Complementary Medicines and Vaccines for Myanmar (2010), Thai Essential Medicines List (2012), WHO Model List of Essential Medicines 18th edition, WHO Model list of Essential Medicines for Children 3rd edition. NLEM Myanmar 2016

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In order to revise, firstly, task force committee (core committee) was developed in June 2013 by Ministry of Health & Sports with following members: (1) Dr. Than Win, Deputy Director General, Department of Public Health, Ministry of Health & Sports as a chairman (2) Dr. Zaw Win, Former Director (Foods and drugs), Department of Foods and Drugs Administration as a member (3) Dr. Hla Myint, Former Director (Medical Care), Department of Medical Services, Ministry of Health & Sports as a member (4) Dr. Nang Hla Hla Win , Professor and Head, Department of Pharmacology , University of Medicine 1, Yangon as a member (5) Dr. Thida Hla, Medical Superintendent, Nay Pyi Taw (1000) bedded, General Hospital, Former Project Manager, Myanmar Essential Medicines project as a secretariat (6) Dr. Thein May Saw, Professor and Head , Department of Pharmacology, University of Medicine, Mandalay, as a member (7) Dr. Khin Mar Myint , Professor and Head (Training) , University of Medicine 1, Yangon as a member NLEM Myanmar 2016

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Dr. Nu Nu Aye, Professor and Head, Department of Pharmacology, University of Medicine 2, Yangon as a member (9) Dr. Theingi Zin, Director (Drugs), Department of Foods and Drugs Administration as a member (10) Dr. Win Win May , (Retd.) Associate Prof, University of Pharmacy, Yangon as a member (11) Dr. Myat Min, Associate Professor, Department of Pharmacology, University of Medicine, Mandalay as a member (12) Dr. Aung Tun, Former Director (Public Health), Former Department of Health as a member (13) Daw Tin Myo Khine, Assistant Director, Department of Foods and Drugs Administration as a member In August 2013, the 1st task force committee meeting was held in the Department of Medical Services, Ministry of Health & Sports. From this meeting result, the modified format of NLEM was developed based on the three major documents such as National List of Essential and Complementary Medicines and Vaccines for Myanmar (2010), WHO Model List of Essential Medicines 18 th edition, WHO Model list of Essential Medicines for Children 3rd edition. NLEM Myanmar 2016

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In July 2013, the modified format of NLEM was distributed to all directors of central hospitals, directors of States and Regions, all project managers to make deletion or changing of items, inclusion or adding of items and justification for every changes via email. In September 2013, workshop for deliberation on evidence based criteria for addition and deletion of items with external consultant from Thailand, Task Force Committee Members, all Professor and Heads (Clinicians) from every discipline was conducted in Ministry of Health & Sports. During the workshop, intensively discussed the current situation of medicines issues which were found in every health facilities and drug resistant condition. Due to difficulty in timely getting of the data concerning the evidence base, cost effectiveness, epidemiological information on disease burden, current usage assessment, and the advice of Thai Consultant, Thai National List of Essential Medicines was decided to be adopted. In March 2014, the 2nd time Task Force Committee meeting was held in the University of Medicine 1, Yangon and reviewed again. Discussion the final draft of NLEM (revised) in Drug Advisory Committee (DAC) meeting was done in November 2014. NLEM Myanmar 2016

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SIGNIFICANT FEATURES OF NLEM (2016) In the National List of Essential Medicines, Complementary Medicines and Vaccines for Myanmar (2010), there were (4) categories such as: E = Essential Medicines for basic health care system E* = Essential Medicines recommended for tertiary referral level C = Complementary Medicines C* = Complementary Medicines recommended for tertiary referral level. Total items were (341). Normally, the NLEM should be updated two yearly according to the WHO guideline. The issue of updating was also discussed and considered based upon the informations came out from various health sectors and programmes, such as updated treatment regime, drug resistant conditions, control drug policy, drugs from programme which were supported by WHO,NGOs, INGOs. The medicines in NLEM (2016) have been categorized as follows: A = everyone (for any doctor) with first choice for the patient B = Alternative to A C = for experts (experienced doctors) NLEM Myanmar 2016

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D = Trained personnel with expert qualifications (drugs to be used in specialized centre) E1 = National Programme Drugs (eg. HIV, TB for Myanmar) E2 = Specialist in specialized centre, kept by authorized body of the hospital, allowed by request (drug is expensive for some rare diseases or conditions, eg., liposomal amphotericin B, digoxin specific antibody) for central procurement The numbers of items in each category are as follow: A = 217 B = 38 C = 139 D = 89 E1 = 41 E2 = 13 Total of (486) medicines are included in NLEM (2016). Some of the items are included in one or two categories (eg. Ampicillin is in category A and C based on dosage form). Therefore, counting the items are (537) by category. [c] – symbol is placed next to an individual medicine or strength of medicine it signifies that there is a specific indication for restricting its use to children. NLEM Myanmar 2016

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[c] – symbol is placed next to the complementary list it signifies that the medicine(s) require (s) specialist diagnostic or monitoring facilities, and/ or specialist medical care, and/ or specialist training for their use in children.

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APPLICATIONS FOR REVIEW AND REVISION OF NLEM (2010) National List of Essential and complementary medicines and vaccines for Myanmar(2010), Thai Essential Medicines Lists (2012), WHO Model List of Essential Medicines 18th edition, WHO Model list of Essential Medicines for Children 3rd edition (Base documents)

Developing the Task Force Committee for review and revision of NLEM 2010

1st time Task Force Committee meeting led by Deputy Director General

Distribution of Modified Format based on NLEM (2010), WHO Model List of Essential Medicines 18th edition, WHO Model list of Essential Medicines for Children 3rd list to all medical directors of central hospitals, directors of States and Regions, all project managers to make deletion or changing of items, inclusion or adding of items and justification

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Workshop for deliberation on evidence based criteria for addition and deletion of items with external consultant from Thailand, Task Force Committee, all Professor and Heads from every discipline

2nd time Task Force Committee meeting

Discussion the final draft of NLEM (revised) in Drug Advisory Committee (DAC) meeting

Final consideration,discussion and summarizing the NLEM draft by Task Force Committee

Submit to the Ministry of Health & Sports for approval

Publishing (2016)

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LIST OF MEDICINES IN NLEM (2016) BY THERAPEUTIC AREAS

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SECTIONS

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ANNEXES TOTAL ITEMS (486) IN NLEM (2016) NO

ITEMS

CATEGORIES

1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17.

4FDC Abacavir Abacavir + Lamivudine ACTH Acarbose Acetazolamide Acetylcysteine Acetylsalicylic Acid Acyclovir Adenosine Albendazole Albumin (Human) Alfacalcidol (1 & Hydroxycholecalciferol) Allopurinol Alprazolam Aluminium Hydroxide Aluminium Hydroxide + Magnesium Hydroxide 18. Amikacin 19. Amiloride NLEM Myanmar 2016

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B E1 E1 E2 C A A C, A A, D A A E2 C A D A A B, C, E1 B


NO 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43.

ITEMS

CATEGORIES

Amino acid solution Aminophylline Amiodarone Amitriptyline (hydrochloride) Amlodipine Amoxicillin Amoxicillin + Clavulanic acid Amphotericin-B Ampicillin Anti-D Immunoglobulin Anastrozole Antisnake Venom Serum (Cobra Antivenom) Antisnake Venom Serum (Viper Antivenom) Antithymocyte globulin Arsenic trioxide Artemether Artemether + Lumefantrine Artesunate Ascorbic acid Asparaginase Atazanavir boosted Lopinavir Atorvastatin Atovaquone + Proguanil Atracurium

NLEM Myanmar 2016

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C A C A A A A C A, C A D A A D D E1 E1 C, E1 A, B C E1 D E1 C


NO 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67.

ITEMS

CATEGORIES

Atropine (Sulphate) Azithromycin Baclofen Bambuterol Barium sulphate BCG Vaccine Beclomethasone (dipropionate) Bendamustine Benzathine pencillin Benzhexol Benzoic acid + Salicylic acid Benzoin Tincture Benzyl benzoate Benzyl penicillin G Betamethasone (valerate) Betamethasone + Neomycin Bevacizumab Bisacodyl Bismuth subnitrate and iodoform Bleomycin-C Boric acid / Spirit Bortezomib Brimonidine Bromocriptine

NLEM Myanmar 2016

61

A, C C B B A A A D A A A A A A B A D A C C A D C C


NO 68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 78. 79. 80. 81. 82. 83. 84. 85. 86. 87. 88. 89. 90. 91.

ITEMS

CATEGORIES

Budesonide inhaler Bupivacaine (Hydrochloride) Busulfan Calamine Calcipotriol ointment Calcium gluconate Capreomycin Carbamazepine Carbimazole Carbocysteine Carboplatin Carvedilol Caspofungin Cefaclor Cefazolin Cefixime Cefotaxime Cefoperazone + Sulbactam Ceftazidime Ceftriaxone Cefuroxime Cephalexin Cetrizine Charcoal

NLEM Myanmar 2016

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A A C A C A E1 A A A C C D, E2 C C C, D B, C D C C, E1 B A A A


NO

ITEMS

92. 93. 94. 95. 96. 97. 98. 99. 100. 101. 102. 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. 115.

Chlorambucil Chloramphenicol Chlorhexidine (Digluconate) (7.5%) Chlorhexidine + Neomycin Chlorine based compound Chloroquine Chloroxylenol Chlorpheniramine Chlorpromazine (Hydrochloride) Chlorthalidone Cholera vaccine Ciclosporin Cinnarizine (Hydrochloride) Ciprofloxacin Cisatracurium Cisplatin Clarithromycin Clindamycin Clobetasol Clofazimine Clomiphene citrate Clomipramine (Hydrochloride) Clonazepam Clopidogrel (Hydrogen sulphate)

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CATEGORIES

63

C A, C A C A A, B, E1 A A A A C C B D C C D B, A A A, E1 C C B B


NO 116. 117. 118. 119. 120. 121. 122. 123. 124. 125. 126. 127. 128. 129. 130. 131. 132. 133. 134. 135. 136. 137. 138.

ITEMS

CATEGORIES

Clotrimazole Cloxacillin Coal tar Codeine phosphate Colchicine Comprox AC+ Solution dichlorometaxylenol Condoms Copper Intra-Uterine Device (Cu-IUD) Co-trimoxazole Capecitabine Cyclophosphamide Cycloserine Cytarabine Dacarbazine Dactinomycin Danazol Dapsone Daunorubicin Dasatinib Deferasirox Deferiprone Deferoxamine Desferrioxamine mesylate

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A, B A A C A A A A A D C C C C C C A, E1 C D C D C C


NO 139. 140. 141. 142. 143. 144. 145. 146. 147. 148. 149. 150. 151. 152. 153. 154. 155. 156. 157. 158. 159. 160. 161. 162.

ITEMS

CATEGORIES

Dexamethasone Dextromethorphan Dextrose Dextrose and sodium chloride Diazepam Diclofenac Diethylcarbamazine Digoxin Digibind Dihydroartemisinin + Piperaquine Diltiazem Dimercaprol Dimethicone Diphenhydramine (hydrochloride) Diphtheria Antitoxin DPT+ Hep B+ Hib Vaccine Diphtheria, Pertussis and Tetanus Vaccine Dipyridamole Dobutamine Docetaxel Domperidone (maleate) Dopamine Doxorubicin Doxycycline

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A, C A A A A A, C A A, D E2 E1 A C A A A A A D B D A A C E1, A


NO

ITEMS

163. 164. 165. 166. 167. 168. 169. 170. 171. 172. 173. 174. 175. 176. 177. 178. 179. 180. 181. 182. 183. 184. 185. 186.

Drotaverine Efavirenz Eltrombopag Enalapril Enoxaparin Ephedrine Epinephrine Epirubicin Ergocalciferol Ergometrine (Hydrogen maleate) Erythromycin Erythropoietin Escitalopram Ethambutol Ethinylestradiol + Levonorgestrel Ethinylestradiol + Norethisterone Ethionamide Etoposide Eusol Felodipine Fenofibrate Fentanyl Ferrous salts (Sulphate, fumarate) Filgrastim

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66

A E1 D A C C A, B D A A A E2 D A A A C C A D C C A D


NO 187. 188. 189. 190. 191. 192. 193. 194. 195. 196. 197. 198. 199. 200. 201. 202. 203. 204. 205. 206. 207. 208. 209. 210.

ITEMS

CATEGORIES

Finasteride Flecainide Fluocinolone acetonide Flucloxacillin Fluconazole Fludarabine Fludrocortisone Flumazenil Flumethasone Fluorometholone 5-Fluorouracil Fluoxetine (hydrochloride) Flutamide Fluticasone Fluticasone Propionate + Salmeterol inhaler Folic acid Folinic acid Formaldehyde Fortified Procaine Penicillin G Framycetin Furosemide Fusidic acid Gabapentin Gadolinium

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D D C A A, C D B D D D C A D A, D C A C A A A A B D D


NO 211. 212. 213. 214. 215. 216. 217. 218. 219. 220. 221. 222. 223. 224. 225. 226. 227. 228. 229. 230. 231. 232. 233. 234.

ITEMS

CATEGORIES

Ganciclovir Gelatin infusion Gemcitabine Gentamicin Glucagon Glutaraldehyde Glycerin suppository Glyceryl trinitrate Glycopyrrolate Granulocyte colony stimulating factor Griseofulvin Haemophilus influenzae B vaccine Haloperidol Halothane Heparin Hepatitis A vaccine Hepatitis B Immunoglobulin Hepatitis B vaccine Trastuzumab (Herceptin) Hexanios Human papilloma virus bivalent vaccine Hydralazine Hydrochlorothiazide Hydrocortisone

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D B D A, C A A A A, C C D A A A C C C C A D D A, E1 A A A, C


NO 235. 236. 237. 238. 239. 240. 241. 242. 243. 244. 245. 246. 247. 248. 249. 250. 251. 252. 253. 254. 255. 256. 257. 258.

ITEMS

CATEGORIES

Hydrogen peroxide Hydroxocobalamin Hydroxycarbamide Hydroxychloroquine [c] Hyoscine (Butylbromide) Ibuprofen Idarubicin Ifosfamide Imatinib Imipenem + Cilastatin Imiquimod Immunoglobulin Indapamide Irinotecan Insulin Insulin Glargine Iopamidol Ipratropium bromide inhaler Isoflurane Isoniazid Isoniazid + Ethambutol Isoniazid + Rifampicin Isoniazid + Rifampicin + Ethambutol Isoniazid + Rifampicin + Pyrazinamide

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A A C B A A D D D C, D D C A D A C D A C A E1 B, E1 E1 B, E1


NO

ITEMS

259. 260. 261. 262. 263. 264. 265. 266. 267. 268. 269. 270. 271. 272. 273. 274. 275. 276. 277. 278. 279. 280. 281. 282.

Isosorbide Dinitrate Isosorbide Mononitrate Itraconazole Ivermectin Japanese Encephalitis vaccine Kanamycin Ketamine (Hydrochloride) Ketoconazole Labetalol Lactulose Lamotrigine Lenalidomide Letrozole Levamisole Levetiracetam Levodopa + Carbidopa Levofloxacin Levonorgestrel Levonorgestrel releasing implant Levothyroxine (Sodium salt) Lignocaine + Epinephrine Lidocaine (Hydrochloride) Lincomycin Linezolid

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A A C C A, B E1 A A C B D D D A D A C, D A C A A A C E2


NO 283. 284. 285. 286. 287. 288. 289. 290. 291. 292. 293. 294. 295. 296. 297. 298. 299. 300. 301. 302. 303. 304. 305. 306.

ITEMS

CATEGORIES

Lipid solution Liposomal Amphotericin Lithium carbonate Loperamide Lopinavir Loratadine Lorazepam Losartan (Potassium) Loteprednol etabonate Leuprolide acetate (Lupron-Depot) Magnesium hydroxide Magnesium oxide Magnesium sulphate Mannitol Measles vaccine Measles/ Mumps/ Rubella vaccine Mebendazole Medroxyprogesterone (Acetate)/ Depot Melfalan Meningococcal vaccine 6-Mercaptopurine Meropenem Mesna Metaraminol

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C E2 A B E1 A A, C B D D A C A, C, E1 A A A A A C C C C D E2


NO 307. 308. 309. 310. 311. 312. 313. 314. 315. 316. 317. 318. 319. 320. 321. 322. 323. 324. 325. 326. 327. 328. 329. 330.

ITEMS

CATEGORIES

Metformin (Hydrochloride) Methadone Methotrexate Methoxypsoralen Ointment Methyldopa Methylated Spirit Methylphenidate Methylprednisolone Methylthioninium chloride Metolazone Metoprolol (Tartrate) Metronidazole Miconazole Midazolam Misoprostol Mitomycin-C Mitoxantrone Mometasone Montelukast Morphine Moxifloxacin Multivitamin and Mineral Mycophenolate mofetil Naloxone

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A D C C A A C C D C A A A C, D A D D D C C D, E1 A D A


NO 331. 332. 333. 334. 335. 336. 337. 338. 339. 340. 341. 342. 343. 344. 345. 346. 347. 348. 349. 350. 351. 352. 353. 354.

ITEMS

CATEGORIES

Naproxen Neomycin Neostigmine (metilsulphate) Netilmicin Nevirapine Niclosamide Nicotinamide Nifedipine retard Nikethamide Nitrofurantoin Nitrous Oxide Nitrous Oxide + Oxygen Norepinephrine Norethisterone enanthate Norfloxacin Nystatin Octreotide Oestrogen Cream Ofloxacin Olanzapine Omeprazole Ondansetron (Hydrochloride) Oral Rehydration Salt Oxaliplatin

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A A B D E1 A B B, C C B C E2 A A A A D E2 E1 C A B A D


NO 355. 356. 357. 358. 359. 360. 361. 362. 363. 364. 365. 366. 367. 368. 369. 370. 371. 372. 373. 374. 375. 376. 377. 378.

CATEGORIES Oxygen A Oxymetazoline C Oxymetholone D Oxytocin A Paclitaxel Powder D Pamidronate D Pantoprazole B Paracetamol A, C P-aminosalicylic acid C, E1 Penicillamine C Perindopril C Permethrin A Pethidine C Phenobarbital A Phenoxymethyl penicillin A Physiological Saline A Phytomenadione A Pilocarpine (Hydrochloride or Nitrate) A Pioglitazone D Piperacillin with tazobactam D Pneumococcal Vaccine A Poliomyelitis Vaccine A Polyethylene Glycol Powder for Solution C Polymyxin B + Neomycin C

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NO 379. 380. 381. 382. 383. 384. 385. 386. 387. 388. 389. 390. 391. 392. 393. 394. 395. 396. 397. 398. 399. 400. 401. 402.

ITEMS

CATEGORIES

Polymyxin + Bacitracin + Neomycin Potassium chloride Potassium citrate Potassium Iodide Potassium permanganate Povidone Iodine Pralidoxime Praziquantel Prazosin (Hydrochloride) Prednisolone Primaquine Procarbazine Prochlorperazine Propafenone Propofol Propranolol Propylthiouracil Protamine sulphate Pyrazinamide Pyridoxine (Hydrochloride) Quinine Rabies Immunoglobulin (Human origin) Rabies Vaccine Ranitidine (Hydrochloride)

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C A A A A A A A B A, C A, E1 C A D C A, C A C A A A B A A


NO 403. 404. 405. 406. 407. 408. 409. 410. 411. 412. 413. 414. 415. 416. 417. 418. 419. 420. 421. 422. 423. 424. 425. 426.

ITEMS

CATEGORIES

Rasburicase Recombinant factor VIII Recombinant factor IX Repaglinide Retinol Ribavirin Riboflavin Rifabutin Rifampicin Rifaximin Ringer Lactate Risperidone Ritonavir boosted Lopinavir Rituximab Rotavirus Vaccine Salbutamol (Sulphate) Salicylic acid Saline Sevoflurane Silver sulfadiazine Simvastatin Sodium bicarbonate Sodium bicarbonate/ glycerin Sodium calcium edetate

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D E1 E1 D A E2 A E1 A, E1 C A C E1 D A A A A C A A A A C


NO 427. 428. 429. 430. 431. 432. 433. 434. 435. 436. 437. 438. 439. 440. 441. 442. 443. 444. 445. 446. 447. 448. 449. 450.

ITEMS

CATEGORIES

Sodium chloride Sodium chromoglycate Sodium fluoride Sodium nitrite Sodium thiosulphate Sorafenib Sotalol Spironolactone Streptokinase Streptomycin Succimer Sulfasalazine Suxamethonium chloride Tacrolimus Tacrolimus/pimecrolimus Tamoxifen Tenofovir Tenofovir + Emtricitabine + Efavirenz Tenofovir + Lamivudine Tenofovir + Lamivudine + Efavirenz Testosterone ester Tetanus immunoglobulin (Human origin) Tetanus vaccine Tetracaine (Hydrochloride)

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A, C C A C C D C A A A D C C D C C E1 E1 E1 E1 C B A D


NO 451. 452. 453. 454. 455. 456. 457. 458. 459. 460. 461. 462. 463. 464. 465. 466. 467. 468. 469. 470. 471. 472. 473.

ITEMS

CATEGORIES

Tetracycline Thalidomide Theophylline Thiamine (Hydrochloride) Thiopental Thioguanine Timolol (maleate) Tincture Opium Tiotropium bromide inhaler Tolnaftate Topiramate Total parenteral nutrition Tramadol Tranexamic acid Travoprost Tretinoin/ all trans retinoic acid Tropicamide Typhoid, Paratyphoid A and B Vaccine with Vi antigen Valproic acid Valganciclovir Vancomycin Varicella vaccine Vecuronium bromide

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A D A A, B C D A E2 B A D C C A D D C A A D D E1 C


NO 474. 475. 476. 477. 478. 479. 480. 481. 482. 483. 484. 485. 486.

ITEMS

CATEGORIES

Verapamil (Hydrochloride) Vinblastine Vincristine Vinorelbine Vitamin B Complex Voriconazole Warfarin Sodium Water for Injection Yellow Fever Vaccine Zidovudine + Lamivudine Zidovudine + Lamivudine + Nevirapine Zinc Sulphate Zoledronic-1A

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A, C C C D A D, E2 C A C E1 E1 A D


ADDING ITEMS (183) TO YEAR (2010) BOOK 1. 2. 3. 4. 5.

ACTH Abacavir + Lamivudine Acarbose Adenosine Aluminium Hydroxide + Magnesium Hydroxide 6. Amino Acid Solution 7. Ampicillin 8. Anastrozole 9. Antithymocyte Globulin 10. Arsenic trioxide 11. Artemether + Lumefantrine 12. Atazanavir boosted Lopinavir 13. Atovaquone + Proguanil 14. Baclofen 15. Bambuterol 16. Bendamustine 17. Betamethasone + Neomycin 18. Bevacizumab 19. Bortezomib 20. Brimonidine 21. Budesonide 22. Busulfan NLEM Myanmar 2016

80

23. Calcipotriol 24. Capecitabine 25. Caspofungin 26. Cefazolin 27. Cefotaxime 28. Cefoperazone + Sulbactam 29. Cholera Vaccine 30. Ciclosporin 31. Cisatracurium 32. Cisplatin 33. Clarithromycin 34. Clobetasol 35. Clonazepam 36. Cytarabine 37. Danazol 38. Dasatinib 39. Deferasirox 40. Deferiprone 41. Desferrioxamine mesylate 42. Dextromethorphan 43. Digibind 44. Dihydroartemisinin + Piperaquine


45. Diphtheria Antitoxin 46. DPT+ Hep B + Hib Vaccine 47. Dipyridamole 48. Docetaxel 49. Drotaverine 50. Eltrombopag 51. Enoxaparin 52. Epirubicin 53. Escitalopram 54. Eusol 55. Felodipine 56. Fenofibrate 57. Filgrastim 58. Flecainide 59. Fluocinolone ac 60. Fludarabine 61. Fludrocortisone 62. Fluocinolone acetonide 63. Fluorometholone 64. Flutamide 65. Fluticasone propionate inhaler 66. Fluticasone propionate + Salmeterol inhaler NLEM Myanmar 2016

81

67. Folinic acid 68. Fusidic acid 69. Gabapentin 70. Gadolinium 71. Ganciclovir 72. Gemcitabine 73. Glucagon 74. Glycerin suppository 75. Glycopyrrolate 76. Granulocyte colony stimulating factor 77. Griseofulvin 78. Hepatitis A vaccine 79. Hexanios 80. Hydroxycarbamide 81. Hydroxychloroquine 82. Ibuprofen 83. Idarubicin 84. Imatinib 85. Imiquimod 86. Immunoglobulin 87. Indapamide 88. Irinotecan 89. Insulin glargine


90. Iopamidol 91. Ipratropium bromide inhaler 92. Isoniazid + Ethambutol 93. Isoniazid + Rifampicin + Ethambutol 94. Isoniazid + Rifampicin + Pyrazinamide 95. Itraconazole 96. Ivermectin 97. Lamotrigine 98. Lenalidomide 99. Letrozole 100. Levetiracetam 101. Lidocaine + Epinephrine 102. Linezolid 103. Liposomal Amphotericin 104. Lithium carbonate 105. Loperamide 106. Loratadine 107. Loteprednol etabonate 108. Leuprolide acetate (Lupron-depot) 109. Magnesium oxide 110. Melfalan NLEM Myanmar 2016

82

111. Meropenem 112. Mesna 113. Metaraminol 114. Methoxypsoralen ointment 115. Methylphenidate 116. Methylthioninium chloride 117. Metolazone 118. Mitomycin - C 119. Mitoxantrone 120. Mometasone 121. Montelukast 122. Moxifloxacin 123. Mycophenolate mofetil 124. Naproxen 125. Nitrofurantoin 126. Nitrous Oxide + Oxygen 127. Octreotide 128. Oestrogen Cream 129. Olanzapine 130. Oxaliplatin 131. Oxymetholone 132. Paclitaxel Powder 133. Pamidronate


134. Pantoprazole 135. P-aminosalicylic acid 136. Perindopril 137. Pioglitazone 138. Piperacillin with tazobactam 139. Pneumococcal Vaccine 140. Polyethylene Glycol Powder for Solution 141. Potassium Iodide 142. Praziquantel 143. Propafenone 144. Protamine Sulfate 145. Rasburicase 146. Recombinant Factor VIII 147. Recombinant Factor IX 148. Repaglinide 149. Rifabutin 150. Rifaximin 151. Risperidone 152. Ritonavir boosted Lopinavir 153. Rituximab 154. Rotavirus Vaccine 155. Saline NLEM Myanmar 2016

156. Sevoflurane 157. Sodium Calcium Edetate 158. Sodium Chromoglycate 159. Sorafenib 160. Sotalol 161. Succimer 162. Tacrolimus 163. Tacrolimus/ pimecrolimus 164. Tenofovir + Emtricitabine + Efavirenz 165. Tenofovir + Lamivudine 166. Tenofovir + Lamivudine + Efavirenz 167. Thalidomide 168. Thioguanine 169. Tiotropium bromide inhaler 170. Tolnaftate 171. Topiramate 172. Total Parenteral Nutrition 173. Trastuzumab (Herceptin) 174. Travoprost 175. Tretinoin/ all trans Retinoic Acid

83


176. Varicella Vaccine 177. Vinorelbine 178. Voriconazole 179. Water for Injection 180. Zidovudine + Lamivudine 181. Zidovudin + Lamivudine + Nevirapine 182. Zinc Sulphate 183. Zoledronic -1 A

NLEM Myanmar 2016

84


DELETING ITEMS (38) FROM YEAR (2010) BOOK 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22.

Atenolol Azathioprine Benzalkonium Chloride Cetrimide Celecoxib Citrate Phosphate Dextrose Adenine 1 Dextran 70 Dextran 40 Didanosine Diethylether Diloxanide furoate Ethinylestradiol Ethosuximide Fluphenazine Glibenclamide Gliclazide Glimepiride Glipizide Hydroxyurea Indinavir Iodine Lamivudine

NLEM Myanmar 2016

85

23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38.

Lugol’s Iodine Mefloquine Metoclopramide Norethisterone Promethazine Pancuronium Pyridostigmine Phenytoin Prostaglandin F-2 alpha Ritonavir Saquinavir Sodium Nitroprusside Stavudine Tinidazole Xylometazoline Zidovudine


TOTAL ITEMS OF 'A' 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20.

Acetazolamide Acetylcysteine Acyclovir Acetylsalicylic Acid Adenosine Albendazole Allopurinol Aluminium Hydroxide Aluminium Hydroxide + Magnesium Hydroxide Aminophylline Amitriptyline Amlodipine Amoxicillin Amoxicillin + Clavulanic Acid Ampicillin Anti -D Immunoglobulin Antisnake Venom Serum (Cobra Antivenom) Antisnake Venom Serum (Viper Antivenom) Ascorbic Acid Atropine

NLEM Myanmar 2016

86

21. Barium Sulfate 22. BCG Vaccine 23. Beclomethasone (Dipropionate) 24. Benzathine Penicillin 25. Benzhexol 26. Benzoic Acid + Salicylic Acid 27. Benzoin Tincture 28. Benzyl Benzoate 29. Benzyl penicillin G 30. Betamethasone + Neomycin 31. Bisacodyl 32. Boric Acid / Spirit 33. Budesonide 34. Bupivacaine 35. Calamine 36. Calcium Gluconate 37. Carbamazepine 38. Carbimazole 39. Carbocysteine 40. Cephalexin 41. Cetrizine


63. 64. 65. 66.

42. Charcoal 43. Chloramphenicol 44. Chlorhexidine (Digluconate) 45. Chlorine based compound 46. Chloroquine 47. Chloroxylenol 48. Chlorpheniramine 49. Chlorpromazine (Hydrochloride) 50. Chlorthalidone 51. Clindamycin 52. Clobetasol 53. Clofazimine 54. Clotrimazole 55. Cloxacillin 56. Coal tar 57. Colchicine 58. Comprox AC + Solution dichlormetaxylenol 59. Condoms 60. Copper Intra-Uterine Device (Cu-IUD) 61. Cotrimoxazole 62. Dapsone NLEM Myanmar 2016

67. 68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 78. 79. 80. 81. 82. 83. 87

Dexamethasone Dextromethorphan Dextrose Dextrose and sodium chloride Diazepam Diclofenac Diethylcarbamazine Digoxin Diltiazem Dimethicone Diphenhydramine (Hydrochloride) Diphtheria Antitoxin DPT + Hep B + Hib Vaccine Diphtheria, Pertussis and Tetanus Vaccine Domperidone (maleate) Dopamine Doxycycline Drotaverine Enalapril Epinephrine Ergocalciferol


84. Ergometrine (Hydrogen maleate) 85. Erythromycin 86. Ethambutol 87. Ethinyl estradiol + Levonorgestrel 88. Ethinyl estradiol + Norethisterone 89. Eusol 90. Ferrous salt (sulfate, fumarate) 91. Flucloxacillin 92. Fluconazole 93. Fluoxetine (hydrochloride) 94. Fluticasone propionate 95. Folic acid 96. Formaldehyde 97. Fortified Procaine Penicillin G 98. Framycetin 99. Furosemide 100. Gentamicin 101. Glucagon 102. Glutaraldehyde 103. Glycerin suppository 104. Glyceryl trinitrate NLEM Myanmar 2016

105. Griseofulvin 106. Haemophilus influenzae B vaccine 107. Haloperidol 108. Hepatitis B vaccine 109. HPV Vaccination 110. Hydralazine 111. Hydrochlorthiazide 112. Hydrocortisone 113. Hydrogen peroxide 114. Hydroxocobalamin 115. Hyoscine (butylbromide) 116. Ibuprofen 117. Indapamide 118. Insulin 119. Ipratropium bromide 120. Isoniazid 121. Isosorbide Dinitrate 122. Isosorbide Mononitrate 123. Japanese Encephalitis vaccine 124. Ketamine (hydrochloride) 125. Ketoconazole 126. Levamisole 127. Levodopa + Carbidopa

88


128. 129. 130. 131. 132. 133. 134. 135. 136. 137. 138. 139. 140. 141. 142. 143. 144. 145. 146. 147. 148. 149.

Levonorgestrel Levothyroxine (sodium) Lignocaine + Epinephrine Lidocaine (hydrochloride) Lithium carbonate Loratadine Lorazepam Magnesium hydroxide Magnesium sulfate Mannitol Measles vaccine Measles/ Mumps/ Rubella vaccine Mebendazole Medroxyprogesterone (acetate)/ Depot Metformin (hydrochloride) Methyldopa Methylated spirit Metoprolol (tartrate) Metronidazole Miconazole Misoprostol Multivitamin and Mineral

NLEM Myanmar 2016

150. 151. 152. 153. 154. 155. 156. 157. 158. 159. 160. 161. 162. 163. 164. 165. 166. 167. 168. 169. 170. 171. 172. 173.

89

Naloxone Naproxen Neomycin Niclosamide Norepinephrine Norethisterone enanthate Norfloxacin Nystatin Omeprazole Oral Rehydration Salt Oxygen Oxytocin Paracetamol Permethrin Phenobarbital Phenoxymethyl penicillin Physiological saline Phytomenadione Pilocarpine (hydrochloride or nitrate) Pneumococcal vaccine Poliomyelitis vaccine Potassium chloride Potassium citrate Potassium iodide


174. Potassium permanganate 175. Povidone Iodine 176. Pralidoxime 177. Praziquantel 178. Prednisolone 179. Primaquine 180. Prochlorperazine 181. Propranolol 182. Propylthiouracil 183. Pyrazinamide 184. Pyridoxine (hydrochloride) 185. Quinine 186. Rabies vaccine 187. Ranitidine (hydrochloride) 188. Retinol 189. Riboflavin 190. Rifampicin 191. Ringer lactate 192. Rotavirus vaccine 193. Salbutamol (sulfate) 194. Salicylic acid 195. Saline 196. Silver sulfadiazine 197. Simvastatin NLEM Myanmar 2016

198. Sodium bicarbonate 199. Sodium bicarbonate/ glycerin 200. Sodium chloride 201. Sodium fluoride 202. Spironolactone 203. Streptokinase 204. Streptomycin 205. Tetanus vaccine 206. Tetracycline 207. Theophylline 208. Thiamine (hydrochloride) 209. Timolol (maleate) 210. Tolnaftate 211. Tranexamic acid 212. Typhoid, Paratyphoid A and B vaccine with Vi antigen 213. Valproic acid 214. Verapamil (hydrochloride) 215. Vitamin B complex 216. Water for injection 217. Zinc sulfate

90


TOTAL ITEMS OF ' B ' 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23.

4FDC Amikacin Amiloride Ascorbic acid Baclofen Bambuterol Betamethasone Cefotaxime Cefuroxime Chloroquine Cinnarizine Clindamycin Clonazepam Clopidogrel Clotrimazole Dobutamine Epinephrine Fludrocortisone Fusidic acid Gelatin infusion Hydroxychloroquine Isoniazid + Rifampicin Isoniazid + Rifampicin + Pyrazinamide

NLEM Myanmar 2016

24. Japanese Encephalitis vaccine 25. Lactulose 26. Loperamide 27. Losartan 28. Neostigmine 29. Nicotinamide 30. Nifedipine retard 31. Nitrofurantoin 32. Ondansetron 33. Pantoprazole 34. Prazosin 35. Rabies immunoglobulin 36. Tetanus immunoglobulin 37. Thiamine 38. Tiotropium bromide

91


TOTAL ITEMS OF ' C ' 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24.

Acarbose Acetylsalicylic acid Alfacalcidol Amikacin Amino acid solution Amiodarone Amphotericin B Ampicillin Artesunate Asparaginase Atracurium Atropine Azithromycin Bismuth subnitrate and iodoform Bleomycin- C Brimonidine Bromocriptine Busulfan Calcipotriol Carboplatin Carvedilol Cefaclor Cefazolin Cefixime

NLEM Myanmar 2016

25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 92

Cefotaxime Ceftazidime Ceftriaxone Chlorambucil Chloramphenicol Chlorhexidine + Neomycin Cholera vaccine Ciclosporin Cisatracurium Cisplatin Clomiphene citrate Clomipramine Codeine phosphate Cyclophosphamide Cycloserine Cytarabine Dacarbazine (DTIC) Dactinomycin Danazol Daunorubicin Deferasirox Deferoxamine Desferrioxamine mesylate


48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. 69. 70. 71.

Dexamethasone Diclofenac Dimercaprol Doxorubicin Enoxaparin Ephedrine Ethionamide Etoposide Fenofibrate Fentanyl Fluocinolone acetonide Fluconazole 5-Fluorouracil Fluticasone propionate + Salmeterol Folinic acid Gentamycin Glyceryl trinitrate Glycopyrrolate Halothane Heparin Hepatitis A vaccine Hepatitis B immunoglobulin Hydrocortisone Hydroxycarbamide

NLEM Myanmar 2016

72. 73. 74. 75. 76. 77. 78. 79. 80. 81. 82. 83. 84. 85. 86. 87. 88. 89. 90. 91. 92. 93. 94. 95. 96. 93

Imipenem + Cilastatin Immunoglobulin Insulin Glargine Isoflurane Itraconazole Ivermectin Labetalol Levofloxacin Levonorgestrel releasing implant Lincomycin Lipid solution Lorazepam Magnesium oxide Magnesium sulfate Melfalan Meningococcal vaccine 6-Mercaptopurine Meropenem Methotrexate Methoxypsoralen Methylphenidate Methylprednisolone Metolazone Midazolam Montelukast


97. 98. 99. 100. 101. 102. 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. 115. 116. 117. 118. 119. 120. 121.

Morphine Nifedipine retard Nikethamide Nitrous oxide Olanzapine Oxymetazoline Paracetamol P-aminosalicylic acid Penicillamine Perindopril Pethidine Polyethylene glycol powder for solution Polymyxin B + Neomycin Polymyxin + Bacitracin + Neomycin Prednisolone Procarbazine Propofol Propranolol Protamine sulfate Rifaximin Risperidone Sevoflurane Sodium calcium edetate 3% Sodium chloride Sodium chromoglycate

NLEM Myanmar 2016

122. 123. 124. 125. 126. 127. 128. 129. 130. 131. 132. 133. 134. 135. 136. 137. 138. 139.

94

Sodium nitrite Sodium thiosulfate Sotalol Sulfasalazine Suxamethonium chloride Tacrolimus / pimecrolimus Tamoxifen Testosterone ester Thiopental Total parenteral nutrition Tramadol Tropicamide Vecuronium bromide Verapamil Vinblastine Vincristine Warfarin sodium Yellow fever vaccine


TOTAL ITEMS OF ' D ' 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24.

Acyclovir Alprazolam Anastrozole Antithymocyte globulin Arsenic trioxide Atorvastatin Bendamustine Bevacizumab Bortezomib Caspofungin Cefixime Cefoperazone + Sulbactam Ciprofloxacin Clarithromycin Capecitabine Dasatinib Deferiprone Digoxin Dipyridamole Docetaxel Eltrombopag Epirubicin Escitalopram Felodipine

NLEM Myanmar 2016

25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 95

Filgrastim Finasteride Flecainide Fludarabine Flumazenil Flumethasone Fluorometholone Flutamide Fluticasone Gabapentin Gadolinium Ganciclovir Gemcitabine Granulocyte colony stimulating factor Trastuzumab (Herceptin) Hexanios Idarubicin Ifosfamide Imatinib Imipenem + Cilastatin Imiquimod Irinotecan Iopamidol Lamotrigine


49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. 69. 70. 71.

72. 73. 74. 75. 76. 77. 78. 79. 80. 81. 82. 83. 84.

Lenalidomide Letrozole Levetiracetam Levofloxacin Loteprednol etabonate Leuprolide Acetate (Lupron-Depot) Mesna Methadone Methylthioninium chloride Midazolam Mitomycin -C Mitoxantrone Mometasone Moxifloxacin Mycophenolate mofetil Netilmicin Octreotide Oxaliplatin Oxymetholone Paclitaxel Pamidronate Pioglitazone Piperacillin with tazobactam

NLEM Myanmar 2016

85. 86. 87. 88. 89.

96

Propafenone Rasburicase Repaglinide Rituximab Sorafenib Succimer Tacrolimus Tetracaine Thalidomide Thioguanine Topiramate Travoprost Tretinoin/ all trans retinoic acid Valganciclovir Vancomycin Vinorelbine Voriconazole Zoledronic -1A


TOTAL ITEMS OF ' E1 ' 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20.

Abacavir Abacavir+Lamivudine Amikacin Artemether Artemether + Lumefantrine Artesunate Atazanavir boosted Lopinavir Atovaquone + Proguanil Capreomycin Ceftriaxone Chloroquine Clofazimine Dapsone Dihydroartemisinin + Piperaquine Doxycycline Efavirenz Human Papilloma Virus Bivalent vaccine Isoniazid + Ethambutol Isoniazid + Rifampicin Isoniazid + Rifampicin + Ethambutol

NLEM Myanmar 2016

97

21. Isoniazid + Rifampicin + Pyrazinamide 22. Kanamycin 23. Lopinavir 24. Magnesium sulfate 25. Moxifloxacin 26. Nevirapine 27. Ofloxacin 28. P-aminosalicylic acid 29. Primaquine 30. Recombinant factor VIII 31. Recombinant factor IX 32. Rifabutin 33. Rifampicin 34. Ritonavir boosted Lopinavir 35. Tenofovir 36. Tenofovir + Emtricitabine + Efavirenz 37. Tenofovir + Lamivudine 38. Tenofovir + Lamivudine + Efavirenz 39. Varicella vaccine 40. Zidovudine + Lamivudine 41. Zidovudine + Lamivudine + Nevirapine


TOTAL ITEMS OF ' E2 ' 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13.

ACTH Albumin Caspofungin Digibind Erythropoietin Linezolid Liposomal Amphotericin Metaraminol Nitrous oxide + Oxygen Oestrogen Ribavirin Tincture opium Voriconazole

NLEM Myanmar 2016

98