Objectively-Measured Sedentary Time and ... - Circulation

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Sep 28, 2015 - performed using SAS software version 9.3 (SAS Institute, Cary, NC). ... behavior was 11.9 hours/day, acco
DOI: 10.1161/CIRCULATIONAHA.115.016938

Objectively-Measured Sedentary Time and Cardiometabolic Biomarkers in U.S. Hispanic/Latino Adults: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Running title: Qi et al.; Sedentary time and CVD risk in Hispanic Adults Qibin Qi, PhD1*; Garrett Strizich, MPH1*; Gina Merchant, MA2; Daniela Sotres-Alvarez, DrPH3; Downloaded from http://circ.ahajournals.org/ by guest on September 15, 2017

Christina Buelna, MA2; Sheila F. Castañeda, PhD2; Linda C. Gallo, PhD4; Jianwen Cai, PhD3; Marc D. Gellman, PhD5; Carmen R. Isasi, MD PhD1; Ashley E. Moncrieft, PhD5; Lisa Sanchez-Johnsen, PhD6; Neil Schneiderman, PhD5; Robert C. Kaplan Kaplan, an,, Ph an PhD D1 1

Dept of Epidemiology and a Population Health, Albert Einstein Einstein College of Medicine, Bronx, NY;

2

Graduate Grad Gr adua ad uate ua te School Sch hoo ool of Public Health, San Diego State Statte University, Sa San Di Diego, ieg ego, CA; 3Collaborative

Studies Sttudies Coor Coordinating ordi dina di nati na t ng Center, Cen ente ter, te r,, Dept Dep eptt of B Biostatistics, i sttat io atis istics, U is University nive vers ve rsit rs ityy off North it Nor orth th Carolina, Carolina na,, Chapel na Chap Ch apel ap ell Hill, Hil ill, l, N NC; C C; 4

Dept of Psyc De Psychology, y hoolo ogy, San Saan Diego Dieg go State Un U University, niveersiity, San Saan Di Dieg Diego, ego, eg o C CA; A;; 5D Dept ept off Psychology, Pssyc ycholo ogy y, Un University niverssitty of M Miami, iamii, Mi ia Miam Miami, amii, F am FL; L 6De L; Dept pt of of Psychiatry, Pssyc ychi hiat hi atry at ry, University ry U iv Un iver ersi er sity si ty of of Il Illi Illinois l no nois is aatt Ch Chic Chicago, i ago ic go,, Ch go Chi Chicago, ic go, icag o IIL L *contributed equally

Address for Correspondence: Qibin Qi, PhD Department of Epidemiology and Population Health Albert Einstein College of Medicine 1300 Morris Park Avenue Bronx, NY 10461 Tel: 718-430-4203 Fax: 718-430-8780 E-mail: [email protected] Journal Subject Term: Epidemiology 1

DOI: 10.1161/CIRCULATIONAHA.115.016938

Abstract

Background—Sedentary behavior is recognized as a distinct construct from lack of moderatevigorous physical activity and is associated with deleterious health outcomes. Previous studies have primarily relied on self-reported data, while data on the relationship between objectivelymeasured sedentary time and cardiometabolic biomarkers are sparse, especially among U.S. Hispanics/Latinos. Methods and Results—We examined associations of objectively-measured sedentary time (via Actical accelerometers for 7 days) and multiple cardiometabolic biomarkers among 12,083 Downloaded from http://circ.ahajournals.org/ by guest on September 15, 2017

participants, aged 18-74 years, from the Hispanic Community Health Study/Study of Latinos. Hispanics/Latinos of diverse backgrounds (Central American, Cuban, Dominican, Mexican, Puerto Rican, and South American) were recruited from 4 U.S. cities between 2008 and and 2011. Sedentary time (