Steve MacMillan, Chairman, President & CEO

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Apr 25, 2018 - of bone densitometry (DXA scans) ... Introducing Cynosure as the newest member of the Hologic family. 15
Steve MacMillan, Chairman, President & CEO Aesthetics Innovation Summit April 25, 2018 1

Transforming women’s health for the last 30 years…

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…and the next 30!

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HOLOGIC

The company that has done more to fight breast and cervical cancer than any other on the planet.

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HISTORY OF PIONEERING INNOVATION •

1987 – Pioneered the introduction of bone densitometry (DXA scans)



1988 – First molecular diagnostic kit for sexually transmitted infections



1996 – FDA approved ThinPrep® Pap test



2011 – Introduced breakthrough 3D mammography years ahead of anyone else 5

GENIUS™ 3D MAMMOGRAPHY™ •

Only the Genius exam finds 20-65% more invasive breast cancers compared to 2D alone



Reduces callbacks by up to 40% compared to 2D alone



Only mammogram that is FDAapproved as superior for women with dense breasts



Have displaced GE and Siemens to become the undisputed market leader 6

CREATED CONSUMER AWARENESS… “I opted for a Genius™ Mammography exam because early detection is what saved my life.” Sheryl Crow Award-winning Singer/Songwriter Breast Cancer Survivor

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CREATED CONSUMER AWARENESS…

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…AND HELPED SECURE REIMBURSEMENT

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CERVICAL CANCER •

Was the #1 cancer killer of women prior to the introduction of Pap screening1



We pioneered the more sensitive and specific ThinPrep® Pap test in 1996



Today, more than 80% of all Pap tests in the U.S. are done via ThinPrep



And cervical cancer is #14 on the list of cancer killers of women2

1) Centers for Disease Control and Prevention; 2) NIH Fact Sheet on cervical cancer.

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BUT THERE’S MORE •

Our Aptima® HPV test is now also the most used screening test in the U.S. for HPV, which causes cervical cancer



And co-testing with Pap + HPV is the MOST EFFECTIVE SCREENING EVER

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FIGHTING FOR WOMEN, EVERYWHERE, EVERY DAY

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OTHER WORLD LEADING PRODUCTS

Molecular testing for sexually transmitted infections

Endometrial ablation for abnormal uterine bleeding

Intrauterine tissue removal (including fibroids & polyps)

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TRANSFORMING WOMEN’S HEALTH THROUGH

Product innovation

Clinical differentiation

Customer support

Patient awareness

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AND NOW Introducing Cynosure as the newest member of the Hologic family

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WHY DID WE BUY CYNOSURE? Love the medical aesthetics space •

Physician interest in cash pay



Strong consumer demand



More effective procedures with less downtime

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CYNOSURE World leader in energy-based therapies

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STRATEGIC GOALS FOR CYNOSURE •

Build the industry’s best commercial organization



SculpSure® heats up



TempSure™ launch



Advance innovation



Women’s health leadership

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WOMEN’S HEALTH BENEFITS FOR PROVIDERS

WOMEN’S HEALTH BENEFITS FOR PROVIDERS •

Diversify revenue



Provide additional services to existing patients



Complement current medical offerings



Attract new patients

Source: Medical Insight, Inc. report on “Energy-Based Women’s Health,” March 2018

WOMEN’S HEALTH BENEFITS FOR PROVIDERS •

Diversify revenue





Provide additional services to existing patients

Nearly 9,000 instruments globally



Complement current medical offerings

Used for more than 1 million procedures



Generating $1 billion in revenue for practitioners

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Attract new patients

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Source: Medical Insight, Inc. report on “Energy-Based Women’s Health,” March 2018

FAVORABLE PATIENT DEMOGRAPHICS •

800 million women ages 50-80 worldwide



46 million in the U.S., plus 2 million breast cancer survivors



Vaginal atrophy affects 10-40% of post-menopausal women



Yet only 20-25% of symptomatic women seek medical attention

Source: Medical Insight, Inc. report on “Energy-Based Women’s Health,” March 2018 22

CLINICAL NEEDS IN WOMEN’S HEALTH •

Genitourinary symptoms of menopause including painful intercourse



Vaginal laxity



Stress urinary incontinence

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OUR COMMITMENT Same as for all of Hologic

Product innovation

Clinical differentiation

Customer support

Patient awareness

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WHAT DRIVES US?



Making a difference



Doing it the right way

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THE DIFFERENCE WE MAKE…

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Come Grow With Us!

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