Textbook of Histology and A Practical Guide

Osteoid. Fig. 6.7 Formation of osteoid and centre of ossification. Stage IV: Formation of calcified matrix and establishment of centre of ossification. The osteoblasts now start secreting alkaline phosphatase resulting in deposition of calcium salts as crystals of hydroxy- apatite in osteoid converting it into calcified bone matrix.
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Textbook of Histology and A Practical Guide

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Textbook of Histology and A Practical Guide

JP Gunasegaran Professor, Department of Anatomy Rajah Muthiah Medical College & Hospital Annamalai University Annamalai Nagar–608 002 Chidambaram, Tamil Nadu, India

ELSEVIER A division of Reed Elsevier India Private Limited Gurgaon (Haryana)

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Textbook of Histology and a Practical Guide, 2/e Gunasegaran

ELSEVIER A division of Reed Elsevier India Private Limited

Mosby, Saunders, Churchill Livingstone, Butterworth Heinemann and Hanley & Belfus are the Health Science imprints of Elsevier.

© 2010 Elsevier First Edition 2007 Second Edition 2010

All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical including photocopying, recording, or any information storage and retrieval system without the prior written permission from the publisher and the copyright holder.

ISBN: 978-81-312-2490-8

Medical knowledge is constantly changing. As new information becomes available, changes in treatment, procedures, equipment and the use of drugs become necessary. The authors, editors, contributors and the publisher have, as far as it is possible, taken care to ensure that the information given in this text is accurate and up-to-date. However, readers are strongly advised to confirm that the information, especially with regard to drug dose/usage, complies with current legislation and standards of practice. Please consult full prescribing information before issuing prescriptions for any product mentioned in the publication.

Published by Elsevier, a division of Reed Elsevier India Private Limited. Registered Office: Gate No. 3, Building No. A-1, 2 Industrial Area, Kalkaji, New Delhi–110 019. Corporate Office: 14th Floor, Building No. 10B, DLF Cyber City, Phase II, Gurgaon–122 002, Haryana, India.

Head, Medical Education: Jalees Farhan Managing Editor (Development): Binny Mathur Copy Editor: Goldy Bhatnagar Manager-Production: N.C. Pant

Laser typeset by Chitra Computers, New Delhi. Printed and bound at Sanat Printers, Kundli, Haryana.

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PREFACE TO THE SECOND EDITION I am extremely thankful to my colleagues and students for their valuable suggestions and also drawing my attention towards minor errors and omissions in the first edition of my book, “Textbook of Histology and a Practical Guide” released in 2007. I am very happy to state that I have tried to incorporate almost all of them as detailed below, without changing the simple, concise and friendly format of the book. 1. Minor errors and omissions have appropriately been amended where ever applicable throughout the book. 2. A brief account on principles of various types of microscopes has been included in the first chapter dealing with histological techniques. 3. Salient features of biological phenomena of the cell is added in the second chapter devoted to epithelial tissue. 4. Characteristics of oral mucosa have been included under Oral Cavity in Chapter 12, detailing digestive system. 5. All photomicrographs have been enlarged for better visualization of labelling inside them besides replacing around 50 old ones with new higher resolution digital pictures. In addition, legends and all illustrations have been aligned side by side for easy and ready comprehension by the students. Similarly the H&E diagrams have also been enlarged. I sincerely hope to receive the same kind of support for this revised edition, which is being released within a short span of three years. At this juncture I wish to thank the staff of Reed Elsevier India Pvt. Ltd., especially Dr. Binny Mathur (Managing Editor) for shouldering the responsibi