Jan 8, 2016 - Although medication nonadherence is a problem that has been known to healthcare providers since the time o
WHITE PAPER
Advances in Medication Adherence:
The Experts Weigh In
White Paper Advances in Medication Adherence: The Experts Weigh In
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INTRODUCTION Although medication nonadherence is a problem that has been known to healthcare providers since the time of Hippocrates and has been a sharp thorn in the side of the healthcare industry for decades, only recently has a stronger lens been focused on more meaningful adherence measurements and more effective approaches to the problem. As more resources are devoted to adherence, it is essential that the right questions are
THE QUESTIONS To better understand the state of the art in medication adherence and where we need to go industry experts to get their answers to three essential questions:
1 What do you think is the most important recent advance in our understanding of the medication adherence problem? 2 Which aspects of the medication adherence problem are most in need of greater research? 3 What is the greatest popular misperception of the adherence problem?
White Paper Advances in Medication Adherence: The Experts Weigh In
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THE EXPERTS Hayden B. Bosworth, PhD Durham Veterans Affairs Medical Center
Duke University Medical Center
Jessica Franklin, PhD Harvard Medical School Brigham and Women’s Hospital
Walid Gellad, MD, MPH
University of Pittsburgh
Ian M. Kronish, MD Columbia University Medical Center
Wei-Hsuan Jenny Lo-Ciganic, PhD, MSCP, MS University of Arizona
Zachary A. Marcum, PharmD, PhD, BCPS University of Washington
Bernard Vrijens, PhD WestRock Healthcare University of Liège
Tucson, AZ
White Paper Advances in Medication Adherence: The Experts Weigh In
Question #1 What do you think is the most important recent advance in our understanding of the medication adherence problem? Dr. Bosworth: and being able to create and deploy programs that are tailored and personalized to
Dr. Franklin:
Dr. Gellad:
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White Paper Advances in Medication Adherence: The Experts Weigh In
Question #1 Continued... Dr. Kronish:
is suboptimal.
For me, the most important recent advance in understanding is that nothing predicts adherence except adherence. Jessica Franklin, PhD
Dr. Lo-Ciganic:
adherence longitudinally.
Dr. Marcum: problem is the use of statistical methods to identify different patterns of medication use
Dr. Vrijens:
as well as in medical practice, contributing to exorbitant healthcare costs. One of the
be managed!
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White Paper Advances in Medication Adherence: The Experts Weigh In
Question #2 Which aspects of the medication adherence problem are most in need of greater research? Dr. Bosworth:
Dr. Gellad:
when they are ingested, inhalers that tell us when actuated, and many other details of
research to identify how adherence data from multiple drugs can be combined together, drug.
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White Paper Advances in Medication Adherence: The Experts Weigh In
Question #2 Continued... Dr. Kronish:
and understudied approach.
We need to better understand the optimal adherence thresholds for improving health outcomes: Is 80% really the best target for all chronic conditions, for all patients? Zachary A. Marcum, PharmD, PhD, BCPS
Dr. Lo-Ciganic: complexity, patient subgroups, target clinical outcomes, or adherence measures and may
Dr. Marcum:
really the best target for all chronic conditions, for all patients?
Dr. Vrijens:
satisfactory adherence to therapeutic drug regimens.
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White Paper Advances in Medication Adherence: The Experts Weigh In
Question #3 What is the greatest popular misperception of the adherence problem? Dr. Bosworth:
That one solution will address this large problem.
Dr. Gellad:
Dr. Kronish:
researchers. Amongst clinicians, a popular misperception is that nonadherence applies to only a few of their own patients. Another popular misperception, particularly among easy.
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White Paper Advances in Medication Adherence: The Experts Weigh In
Question #3 Continued... Dr. Lo-Ciganic:
technology.
Health systems need to evolve to meet the challenge of achieving satisfactory adherence to therapeutic drug regimens. Bernard Vrijens, PhD
Dr. Marcum:
Dr. Vrijens:
There is often confusion among the three elements of medication adherence: initiation addition, the use of biased and/or sparse measures of medication adherence misleads
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White Paper Advances in Medication Adherence: The Experts Weigh In
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COMMENTARY BY DR. KATRINA FIRLIK, CHIEF MEDICAL OFFICER AND CO-FOUNDER, HEALTHPRIZE TECHNOLOGIES medication adherence research is a dynamic enterprise
the idea that demographics might predict adherence, and
their physician told them to stop the medication due to a
medication nonadherence is more complex than it might
Another theme is the importance of measurement and promise to help us better understand adherence patterns
experts as well. And how should patients be targeted?
outcomes and decrease costs.
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