the impact of collaboration - Cancer Research UK

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THE IMPACT OF COLLABORATION: THE VALUE OF UK MEDICAL RESEARCH TO EU SCIENCE AND HEALTH

Research by Peter Varnai, Maike Rentel, Anoushka Davé, Marika De Scalzi, Wia Timmerman, Cristina Rosemberg-Montes, Paul Simmonds Technopolis Group (May 2017) Study co-funded by The Academy of Medical Sciences (AMS), Arthritis Research UK, the Association of Medical Research Charities (AMRC), the British Heart Foundation (BHF), Cancer Research UK (CRUK), the Medical Research Council (MRC), MQ: Transforming Mental Health and Wellcome.

This report together with the appendices, case studies and executive summary are available at cruk.org/UKandEUresearch

The impact of collaboration: the value of UK medical research to EU science and health A review of existing evidence and views from the EU Technopolis Group (May 2017) Peter Varnai Maike Rentel Anoushka Davé Marika De Scalzi Wia Timmerman Cristina Rosemberg-Montes Paul Simmonds The funders of the research wrote the executive summary based on the report by the Technopolis Group. 2

CONTENTS 1 EXECUTIVE SUMMARY

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1.1 Contribution of UK expertise to EU collaborations, advisory bodies and policies

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1.2 Development of pan-EU clinical trials

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1.3 The role of the UK’s world class medical research facilities in EU science

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1.4 Development of new therapies and medical technologies

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1.5 An attractive training environment for early-career researchers

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1.6 Conclusion

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2 BACKGROUND18 3 CONTRIBUTION OF UK EXPERTISE TO EU COLLABORATIONS, ADVISORY BODIES AND POLICIES

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3.1 Introduction19 3.2 Collaboration20 3.3 Leadership27 4 DEVELOPMENT OF PAN-EU CLINICAL TRIALS

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4.1 Introduction 

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4.2 Pan-EU clinical trials

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4.3 Clinical trial methodology

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4.4 Clinical trial infrastructure

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5 THE ROLE OF THE UK’S WORLD CLASS MEDICAL RESEARCH FACILITIES IN EU SCIENCE

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5.1 Introduction 

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5.2 Cohort studies

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5.3 Bioinformatics infrastructure

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5.4 Biorepositories45 5.5 Research facilities

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6 DEVELOPMENT OF NEW THERAPIES AND MEDICAL TECHNOLOGIES

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6.1 Introduction47 6.2 Impact on public health and patients

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6.3 Translating research into innovative therapies

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6.4 Patient involvement in research

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6.5 European clinical and public health guideline

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7 AN ATTRACTIVE TRAINING ENVIRONMENT FOR EARLY-CAREER RESEARCHERS

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7.1 UK research institutions in the health and life sciences 

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7.2 The role of the UK in training early career researchers from other EU countries

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7.3 Training biomedical students from other EU countries

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8 CONCLUDING REMARKS

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ENDNOTES

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TABLES Table 1 Table 2

Top 10 organisations in terms of Marie Sklodowska-Curie action fellowships (FP7, 2007-2013)

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UK contributions as percentages of internationally co-authored papers in the biomedical field to national health advisory committee members’ papers of other EU countries 

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Table 3

Use of UK research infrastructures by European researchers

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Table 4

Number of Research Excellence Framework impact case studies reporting an impact on health

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Table 5

Examples of UK research with health impact in EU memb