WEEKLY EPIDEMIOLOGICAL REPORT WEST NILE VIRUS ...

Nov 14, 2011 - and ii) the Department of Microbiology, School of Medicine, University of Athens .... poultry in the area of Central Macedonia with the veterinary.
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KEELPNO, Weekly report 14–Nov–2011

HELLENIC CENTRE FOR DISEASE CONTROL AND PREVENTION (KEELPNO) MINISTRY OF HEALTH AND SOCIAL SOLIDARITY

WEEKLY EPIDEMIOLOGICAL REPORT WEST NILE VIRUS INFECTION, GREECE - 14 November 2011 This weekly epidemiological report aims to present briefly the reported cases of West Nile Virus (WNV) infection in Greece for the period 2011. Data presented in this report are derived from the notifications of laboratory confirmed cases sent to the Hellenic Centre for Disease Control and Prevention (KEELPNO) by their treating physicians. Laboratory data are also included from i) the Reference Laboratory for Arboviruses, Aristotelian University of Thessaloniki and ii) the Department of Microbiology, School of Medicine, University of Athens iii) the Department of Microbiology, Infectious Disease Hospital of Thessaloniki. The Department of Epidemiological Surveillance and Intervention of KEELPNO undertakes a verification procedure through communication with the treating physicians and the patients, if necessary. From the beginning of 2011 until 14/11/2011 (16:00), 101 laboratory confirmed cases of WN infection were reported, of which 76 presented with neuro-invasive disease (encephalitis and/or meningitis and/or acute flaccid paralysis) and 25 cases with mild symptoms (fever and/or rash). Eight deaths occurred in patients over 65 years of age with underline diseases (Table 1). One out of the 76 neuro-invasive cases is considered imported, as the patient was in Albania throughout the incubation period. Another neuro-invasive case was diagnosed in France. However, this patient was in Greece throughout the incubation period. The last reported case had onset of symptoms on 18 October 2011. No other cases have been reported to date. A new update will be posted on the website if new cases occur. However, surveillance of the disease will continue throughout the year. Table 1. Number of cases with laboratory confirmed WNV infection, Greece, period 2011 until 14.11.2011 (16:00)

Cases diagnosed by 14.11.2011 (16:00)

[1] [2]

Number of cases with central nervous [1] system manifestations

Number of cases without central nervous system manifestations

Total number of cases

Number of [2] deaths

76

25

101

8

Cases presenting with encephalitis and/or meningitis The number of deaths is included in the total number of cases

KEELPNO, Weekly report 14–Nov–2011

The analysis that follows refers to the 75 cases of WN neuro-invasive disease (WNND) presenting with encephalitis and/or meningitis or acute flaccid paralysis and without reported travel history to another country during the incubation period.

Figure 1 shows the reported WNND cases by date of symptom onset. The first case for 2011 reported onset of symptoms in week 28/2011 (11-17/7/2011). Figure 1. Number of laboratory confirmed WNND cases by week of symptom onset. Period 2011, until 14.11.2011 (16.00)*

* The dotted line represents the number of WNND cases reported in 2010. Each box represents one case reported in period 2011.

Patient age ranges between 2–89 years old (median age: 70 years).

KEELPNO, Weekly report 14–Nov–2011

Table 2 shows the geographic distribution (regional units) of the notified neuro-invasive cases. Of note is the fact that the patient’s place of residence is a crude indicator of the area of virus circulation. Table 2. Place of residence of patients with WNND. Period 2011, until 14.11.2011 (16.00) Regional Unit of Residence

Number of cases

Incidence per 100.000 population

Karditsa

8

6,89

Larisa

12

4,20

Viotia

5

3,99

Trikala

5

3,83

East Attica

15

3,71

Pella